Results 121 to 130 of about 74,517 (259)
Absolute Rates of Globin Chain Synthesis in Thalassemia [PDF]
, 1968 Arthur Bank +3 more
openalex +1 more source
Potential New Expression Biomarkers for Anorexia Nervosa
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 4, June 2025.ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi +8 more
wiley +1 more source
TRANSPORT OF GLOBIN BY THE RENAL GLOMERULUS [PDF]
, 1964 Max G. Menefee +3 more
openalex +1 more source
Is Enhancer Function Driven by Protein–Protein Interactions? From Bacteria to Leukemia
BioEssays, Volume 47, Issue 6, June 2025.Enhancers are key regulatory elements that are conceptually conserved from bacteria to humans. Enhancer dysregulation is common in cancers, including leukemia. We argue that highly specific protein–protein interactions, including transcription factors, mediate enhancer‐promoter proximity to allow enhancer‐bound factors to directly act on RNA polymerase
Nicholas T. Crump, Thomas A. Milne
wiley +1 more source
The haem–globin linkage. 1. Artificial haemoglobins from haematins lacking free carboxyl groups [PDF]
, 1960 J. E. O'hagan
openalex +1 more source
CRISPR/Cas9-mediated γ-globin expression upregulation in HEK293T cells
Guangxi Yike Daxue xuebaoObjective To edit the γ-globin promoter of HEK293T cells using the CRISPR/Cas9 technology to upregulate γ-globin and explore the feasibility of using gene editing technology for the treatment of β-thalassemia.
HUANG Xianjuan, LAI Yongrong, LI Jing
doaj +1 more source
THE SYNTHESIS OF HEME AND GLOBIN IN THE MATURING HUMAN ERYTHROID CELL* [PDF]
, 1961 David G. Nathan +2 more
openalex +1 more source
Epigenetic modulations on the fetal hemoglobin induction [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2012 In recent years of experience fetal hemoglobin (HbF) induction considers as novel therapeutic approach for β-thalassemia and sickle cell in therapeutic approaches.
Najmaldin Saki +4 more
doaj
The haem-globin linkage. 2. Artificial myoglobins from haematins lacking free carboxyl groups [PDF]
, 1960 J. E. O'hagan, Philip George
openalex +1 more source
HemaSphereα‐Thalassemia represents one of the most important genetic modulators of β‐hemoglobinopathies. During this last decade, the ongoing interest in characterizing genotype–phenotype relationships has yielded incredible insights into α‐globin gene regulation ...
Jim Vadolas +4 more
doaj +1 more source