Results 181 to 190 of about 151,779 (318)
Erythroleukemia (K562) cells contain a functional beta-globin gene.
M Donovan-Peluso +3 more
openalex +2 more sources
Abstract A comprehensive understanding of the biophysical parameters that dictate high catalytic efficiency in enzymes is essential for advancing both fundamental enzymology and its applications. Experimental evidence suggests that protein dynamics play a pivotal role in transiently shaping active site configurations, facilitating the efficient ...
Hanzi Gao +7 more
wiley +1 more source
Mitochondrial respiratory supercomplex assembly factor COX7RP improves metabolic homeostasis and contributes to lifespan extension in mice. The overexpression of COX7RP reduces white adipose tissue mass and downregulates senescence‐associated secreted phenotype‐related genes in the tissue, suggesting that COX7RP plays a role in preventing aging through
Kazuhiro Ikeda +6 more
wiley +1 more source
Opposite to the age trend in healthy children, cerebral blood flow increases with age in children with sickle cell anaemia. Early treatment with hydroxyurea (hydroxycarbamide) may help slow this abnormal trend and protect brain functions.
Ping Zou Stinnett +10 more
wiley +1 more source
Advances in Gene Therapy for Inherited Haemoglobinopathies. [PDF]
Gaspar AB, Gaspar HB.
europepmc +1 more source
QUANTITATIVE CONCORDANCE BETWEEN GLOBIN mRNAs AND SYNTHESIS OF FETAL HEMOGLOBIN (HbF) AND ADULT HEMOGLOBIN (HbA) DURING HYPOXEMIC STRESS ERYTHROPOIESIS. † 1293 [PDF]
Krishna G. Peri +2 more
openalex +1 more source

