Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
Profiling structural variations of the α-globin gene cluster by the single molecule real-time sequencing: remarkable diversity of the spectrum with rare and novel variants identified in a large Chinese cohort. [PDF]
Wei D +11 more
europepmc +1 more source
In vitro differential expression of human globin genes.
Yoshiro Wada, Constance Tom Noguchi
openalex +1 more source
Abstract Objectives Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer‐related death. Colonoscopy (CO) is the gold standard for screening, but its invasive nature and low adherence limit its use. Second‐generation capsule endoscopy (CCE‐2) emerges as a non‐invasive alternative.
Cauã Ferreira Câmara +8 more
wiley +1 more source
Downregulation of ZBTB7A/LRF increases fetal hemoglobin expression in β<sup>0</sup>-thalassemia/hemoglobin E erythroid cells. [PDF]
Chumchuen S +9 more
europepmc +1 more source
Iron‐related intercellular communication in the liver: Main players and mechanisms
Iron exchange between liver cell types is vital for organism health, yet its mechanisms remain poorly understood. In this review, we address intercellular communication governing hepatic iron regulation across different liver diseases. We summarize recent insights into how hepatocytes, macrophages, endothelial and stellate cells coordinate iron storage,
Óscar Fonseca +4 more
wiley +1 more source
Gene Therapy of Beta Hemoglobinopathies. [PDF]
Testa U, Pelosi E, Castelli G.
europepmc +1 more source
Changes in Globin Synthesis With Erythroid Cell Maturation in Sickle Thalassemia [PDF]
A Bank +5 more
openalex +1 more source
Development of the neurohypophysis: A major neuroendocrine interface
Abstract The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis.
Athul R. Ramesh +5 more
wiley +1 more source
Case series: a rare dominant form of β-thalassemia successfully treated by luspatercept. [PDF]
Allard PN, Kulozik AE, Kunz JB.
europepmc +1 more source

