Results 201 to 210 of about 151,779 (318)

Mechanism of CO2 and NH3 transport through human aquaporin 1: Evidence for parallel CO2 pathways

The Journal of Physiology, Volume 604, Issue 1, Page 336-365, 1 January 2026.
Abstract figure legend The figure illustrates the permeation pathways for CO2, NH3 and H2O through AQP1. The panel on the left, with the wild‐type protein under control conditions, CO2 moves through monomeric pores (2 of 4 shown) but predominantly via an alternate pathway (perhaps the central pore of the tetramer).
Raif Musa‐Aziz, R. Ryan Geyer, Seong‐Ki Lee, Fraser J. Moss, Walter F. Boron   +4 more
wiley   +1 more source

Revisiting hemoglobin constant spring: molecular insights, pathophysiological mechanisms, and clinical perspectives. [PDF]

Orphanet J Rare Dis
Wongkhammul N, Khamphikham P, Maneekesorn S, Charoenkwan P.   +3 more
europepmc   +1 more source

Epistatic Interactions Among Co‐Inherited Malaria‐Protective Red Blood Cell Polymorphisms and Their Effects Across the Infection‐Mortality Spectrum in Endemic Populations: A Systematic Review

Anemia, Volume 2026, Issue 1, 2026.
Background Malaria remains a major global health burden, with red blood cell (RBC) polymorphisms conferring partial protection. However, the epistatic interactions among co‐inherited RBC polymorphisms are poorly understood. We aimed to characterise how epistatic interactions among malaria‐protective RBC polymorphisms modify risk across the infection‐to‐
George Paasi, Ruth Namazzi, Glorias Asiimwe, Grace Ndeezi, Joseph Rujumba, Christine Sekaggya-Wiltshire, Ezekiel Mupere, Ian Guyton Munabi, Sarah Kiguli, Richard Idro, Peter Olupot-Olupot, Duran Canatan   +11 more
wiley   +1 more source

Cooperative ligand binding in a bacterial heme-based oxygen sensor. [PDF]

J Biol Chem
Hoque NJ, Pope SR, Venkatakrishnan V, Olori DO, Brady NA, Patterson DC, Anand GS, Liu Y, Boal AK, Weinert EE.   +9 more
europepmc   +1 more source

Importance of the 3'UTR region in globin synthesis: identification of two novel HBA1 mutations causing α-Thalassemia. [PDF]

Ann Hematol
Benito SF, Abío M, Bardón-Cancho EJ, Nieto JM, Ortega B, González FA, Villegas A, Benavente C, Ropero P.   +8 more
europepmc   +1 more source

Peptide nucleic acid (PNA) binding-mediated induction of human  -globin gene expression [PDF]

, 1999
G. Wang, Xiaobo Xu, Betty S. Pace, David A. Dean, Peter M. Glazer, Pak H. Chan, Steven R. Goodman, Inna N. Shokolenko   +7 more
openalex   +1 more source

Hemoglobin Phenotype Distribution Among Future Healthcare Providers: A Descriptive Cross‐Sectional Study at a Ghanaian Health Sciences University

The Scientific World Journal, Volume 2026, Issue 1, 2026.
Background Abnormal hemoglobin phenotypes are prevalent genetic alterations in Ghana. Testing medical laboratory science students for these variants provides personal health information while enhancing their professional education as future healthcare providers.
Richard Vikpebah Duneeh, Debrah Sheila Yesuenam Ama, Mercy Adzo Klugah, Emmanuel Allotey, Elliot Elikplim Akorsu, Precious Kwablah Kwadzokpui, Kenneth Ablordey, Kalyani Sen   +7 more
wiley   +1 more source

Comparative analysis of CRISPR-Cas9, lentiviral transduction, and base editing for sickle cell disease in a murine model. [PDF]

Blood Adv
Butt H, Sathish S, London E, Le A, Li Q, Gudmundsdottir B, Lee DY, Burke EV, Yates BP, Liu DR, Hsieh M, Leonard A, Eaton WA, Uchida N, Pierciey FJ, Newby GA, Tisdale JF, Demirci S.   +17 more
europepmc   +1 more source

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

, 2015
Maria Armila Ruiz, Angela Rivers, Vinzon Ibañez, Kestis Vaitkus, Nadim Mahmud, Joseph DeSimone, Donald Lavelle   +6 more
openalex   +1 more source

Requirements for utilization of CREB binding protein by hypersensitive site two of the beta-globin locus control region [PDF]

, 2002
K. D. Johnson
openalex   +1 more source