Results 121 to 130 of about 17,498 (250)

Sturgeons: An Evolutionary Insight to The α-globin Protein Speciation and Diversification [PDF]

open access: gold, 2022
Shohreh Ariaeenejad   +4 more
openalex   +1 more source

Future Perspective On Materials, Electrochemistry, and Cell Concepts for Redox‐Mediated CO2 Direct Air Capture Scenarios

open access: yesChemistryEurope, Volume 4, Issue 1, January 2026.
Direct air capture (DAC) of carbon dioxide (CO2) emerges as a key strategy for climate crisis mitigation. Redox‐mediated electrochemical carbon capture offers a promising route for energy‐efficient DAC. This perspective discusses recent advances in the field, highlighting key challenges, such as oxygen interference at low CO2 concentrations, and ...
Tilmann J. Neubert, Martin Oschatz
wiley   +1 more source

The 5′ Cap Epitranscriptome and Beyond: Natural and Engineered 5′ Cap Modifications for Optimizing mRNA Therapeutics and Functional Studies

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
5′ Cap modifications can be introduced via enzymes or chemical synthesis. Natural and non‐natural 5′ cap structures affect mRNA properties, including translation (T), stability (S), and/or immunogenicity (I). Eukaryotic mRNAs made by in vitro transcription have emerged as medical modalities for vaccination and protein replacement therapy. The 5′ cap is
Greta Charlotte Dahm   +3 more
wiley   +1 more source

MeMAGEN: A Phase IIa/IIb open‐label trial of memantine testing safety and tolerability in sickle cell patients

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren   +7 more
wiley   +1 more source

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss   +3 more
wiley   +1 more source

A Rational Approach to Pharmacotherapy in Pregnancy

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen   +2 more
wiley   +1 more source

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