Top‐Down Proteomics Study of Aging and Sexual Dimorphism of Zebrafish Brains
Journal of Mass Spectrometry, Volume 61, Issue 1, January 2026.ABSTRACT Aging significantly impacts brain function and increases susceptibility to neurodegenerative diseases, with notable sex dimorphism observed in aging‐related dementia, such as Alzheimer's disease. To better understand the molecular mechanisms of aging and dementia, it is essential to globally and accurately characterize biomolecules (e.g ...
Mehrdad Falamarzi Askarani +6 more
wiley +1 more source
Hemoglobin profile and molecular characteristics of the complex interaction of hemoglobin Doi-Saket [α9(A7) asn > lys, HBA2:c.30C > a], a novel α2α1 hybrid globin variant, with hemoglobin E [β26(B8) Glu > lys, HBB:c.79G > A] and deletional α + -thalassemia in a Thai family [PDF]
, 2023 Sitthichai Panyasai +2 more
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Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.In this study, WES analysis was performed on patients with DD/ID, global developmental delay, epilepsy, and multiple congenital anomalies who could not be diagnosed through karyotype, CMA, and other examinations. Nineteen pathogenic/likely pathogenic (P/LP) variants were identified in 19 patients, and with the confirmation made in the parents and ...
Nejmiye Akkus +5 more
wiley +1 more source
Single-copy transduction and expression of human gamma-globin in K562 erythroleukemia cells using recombinant adeno-associated virus vectors: the effect of mutations in NF-E2 and GATA-1 binding motifs within the hypersensitivity site 2 enhancer [published erratum appears in Blood 1995 Feb 1;85(3):862] [PDF]
, 1993 JL Miller +4 more
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An Important Proportion of Genital Samples Submitted for Chlamydia trachomatis Detection by PCR Contain Small Amounts of Cellular DNA as Measured by β-Globin Gene Amplification [PDF]
, 2000 François Coutlée +5 more
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Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.Current carrier screening primarily focuses on high detection rates and broad testing ranges. We approach the issue from the perspective of a community physician, evaluating the suitability of carrier screening based on factors such as cost, ease of report interpretation, and compliance issues.
Zhihui Wang +6 more
wiley +1 more source
Purification and characterization of recombinant human translation initiation factor eIF3
Protein Science, Volume 35, Issue 1, January 2026.Abstract Eukaryotic translation initiation factor 3 (eIF3) is an essential factor in protein synthesis. In mammals, it is a ~800 kDa complex composed of 12–13 subunits. Biochemical and mechanistic studies of the function of eIF3 and its individual subunits in translation require purified eIF3.
Irene Diaz‐Lopez +4 more
wiley +1 more source
Correction: The replication timing program of the Chinese hamster β-globin locus is established coincident with its repositioning near peripheral heterochromatin in early G1 phase [PDF]
, 2001 openalex +1 more source