Results 31 to 40 of about 33,604 (226)

Thin glomerular basement membrane disease [PDF]

Kidney International, 2001
Isolated microscopic hematuria that begins in childhood and is of glomerular origin has a rather limited differential diagnosis, with Alport syndrome, IgA nephropathy, and benign familial hematuria as the most prevalent conditions. In a series of 322 children with persistent hematuria for longer than 6 months, biopsies were classified as IgA ...
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Clinical Significance of Zero-Time Renal Transplant Biopsies and Thin Glomerular Basement Membranes in Zero-Time Renal Transplant Biopsies

Acta Clinica Croatica, 2021
Aim. To investigate morphological findings of zero-time biopsies analyzed at the Department of Nephropathology and Electron Microscopy, Dubrava University Hospital, Zagreb. Materials and methods.
Petar Šenjug, Matija Horaček, Bojana Maksimović, Ksenija Vučur, Ivica Horvatić, Nikola Zagorec, Mladen Knotek, Danica Galešić Ljubanović   +7 more
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Atypical anti-glomerular basement membrane disease [PDF]

Clinical Kidney Journal, 2015
Anti-glomerular basement membrane (anti-GBM) disease classically presents with aggressive necrotizing and crescentic glomerulonephritis, often with pulmonary hemorrhage. The pathologic hallmark is linear staining of GBMs for deposited immunoglobulin G (IgG), usually accompanied by serum autoantibodies to the collagen IV alpha-3 constituents of GBMs ...
Troxell, Megan L., Houghton, Donald C.
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Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes. [PDF]

PLoS ONE, 2013
BackgroundPodocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified Myo1e as a key molecular component of the podocyte cytoskeleton.ResultsMyo1e mRNA and protein was expressed in human and mouse ...
Jianhua Mao, Dayan Wang, Parikka Mataleena, Bing He, Dadi Niu, Kan Katayama, Xiangjun Xu, Juha Rm Ojala, Wenjing Wang, Qiang Shu, Lizhong Du, Aimin Liu, Timo Pikkarainen, Jaakko Patrakka, Karl Tryggvason   +14 more
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Glomerulonephritis associated with systemic sclerosis: a case report

Journal of Medical Case Reports, 2023
Background Systemic sclerosis is a multiorgan autoimmune disease that can overlap with other rheumatologic disorders; however, co-occurrence with antineutrophil cytoplasmic antibody-associated vasculitis is rare.
Sepehr Nayebirad, Alireza Ramandi, Fatemeh Nili, Reza Atef-Yekta, Zahra Tamartash, Samira Salehi, Hoda Kavosi   +6 more
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ANCA-mediated crescentic glomerulonephritis with linear deposition of IgG along the glomerular basement membrane

Saudi Journal of Kidney Diseases and Transplantation, 2014
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on ...
Wiroon Sangsiraprapha, Luan Truong, Sreedhar Mandayam   +2 more
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Atypical Anti-Glomerular Basement Membrane Disease

Kidney International Reports, 2023
La maladie atypique de la membrane basale anti-glomérulaire (anti-GBM) est caractérisée par un dépôt d'immunoglobuline G (IgG) linéaire le long du GBM sans anticorps IgG anti-GBM circulants. Par rapport à la maladie anti-GBM classique, la maladie anti-GBM atypique a tendance à être plus douce avec une évolution plus indolente dans certains cas. De plus,
Joyita Bharati, Yihe Yang, Purva Sharma, Kenar D. Jhaveri   +3 more
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Glomerular Basement Membrane Protein Expression and the Diagnosis and Prognosis of Autosomal Dominant Alport Syndrome

Kidney Medicine, 2019
Alport syndrome is a hereditary glomerular nephritis associated with hearing loss and eye abnormalities and is classified as X-linked Alport syndrome, autosomal recessive Alport syndrome, and autosomal dominant Alport syndrome.
Taro Akihisa, Masayo Sato, Yoshie Wakayama, Sekiko Taneda, Shigeru Horita, Orie Hirose, Shiho Makabe, Hiroshi Kataoka, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Kosaku Nitta, Toshio Mochizuki   +12 more
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Membranous nephropathy followed by anti-glomerular basement disease: A case report and review of clinical presentation and treatment

SAGE Open Medical Case Reports, 2018
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer, Matthias Martin Gaida, Rüdiger Waldherr, Christian Nusshag, Florian Kälble, Martin Zeier   +5 more
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ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

Disease Models & Mechanisms, 2016
Collagen IV is a major component of basement membranes, and mutations in COL4A1, which encodes collagen IV alpha chain 1, cause a multisystemic disease encompassing cerebrovascular, eye and kidney defects.
Frances E. Jones, Matthew A. Bailey, Lydia S. Murray, Yinhui Lu, Sarah McNeilly, Ursula Schlötzer-Schrehardt, Rachel Lennon, Yoshikazu Sado, David G. Brownstein, John J. Mullins, Karl E. Kadler, Tom Van Agtmael   +11 more
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