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Anti-Glomerular Basement Membrane Disease

Definitions, 2020
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement ...
A. Rees
semanticscholar   +1 more source

A nanoporous surface is essential for glomerular podocyte differentiation in three-dimensional culture [PDF]

International Journal of Nanomedicine, 2016
Cristina Zennaro,1 Maria Pia Rastaldi,2 Gerald James Bakeine,3 Riccarda Delfino,1 Federica Tonon,1 Rossella Farra,4 Gabriele Grassi,1,5 Mary Artero,6 Massimo Tormen,7 Michele Carraro1 1Department of Medical, Surgical and Health Sciences, University of ...
Zennaro C, Rastaldi MP, Bakeine GJ, Delfino R, Tonon F, Farra R, Grassi G, Artero M, Tormen M, Carraro M   +9 more
doaj   +3 more sources

Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation

BMC Nephrology, 2023
Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou, Chaojun Qi, Minfang Zhang, Xiaotao Hou, Zhaohui Ni   +4 more
doaj   +1 more source

Etanercept-Induced Anti-Glomerular Basement Membrane Disease

Case Reports in Nephrology and Dialysis, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi, Henry H.L. Wu, Rajkumar Chinnadurai, Arvind Ponnusamy   +3 more
doaj   +1 more source

Prevalence of clinical, pathological and molecular features of glomerular basement membrane nephropathy caused by COL4A3 or COL4A4 mutations: a systematic review

Clinical Kidney Journal, 2020
Background Patients heterozygous for COL4A3 or COL4A4 mutations show a wide spectrum of disease, extending from familial isolated microscopic haematuria, as a result of thin basement membranes (TBMs), to autosomal dominant Alport syndrome (ADAS) and end ...
Andreas M. Matthaiou, Tsielestina Poulli, C. Deltas   +2 more
semanticscholar   +1 more source

Anti-glomerular basement membrane disease [PDF]

Kidney International, 2003
Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD, Harrington, JT, Dasgupta, I, Feehally, J, Rees, A, Hughes, J, Singh, A, Savage, C, Salama, A, Winearls, C, Tomson, C, Mathieson, P, Oliveira, D, Nelson, W   +13 more
openaire   +4 more sources

Mechanisms of Podocyte Detachment, Podocyturia, and Risk of Progression of Glomerulopathies

Kidney Diseases, 2020
Background: Glomerulopathies are the main cause of ESRD. Primary or secondary causes of glomerular diseases comprise more than 70% of cases that end up in renal replacement therapies.
Hernán Trimarchi
doaj   +1 more source

The glomerular basement membrane [PDF]

Experimental Cell Research, 2012
The kidney's glomerular filtration barrier consists of two cells-podocytes and endothelial cells-and the glomerular basement membrane (GBM), a specialized extracellular matrix that lies between them. Like all basement membranes, the GBM consists mainly of laminin, type IV collagen, nidogen, and heparan sulfate proteoglycan.
openaire   +3 more sources

Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel, Patel Dhruval, Tunkel Allan R   +2 more
doaj   +1 more source

Permselectivity of the glomerular wall examined with iron compound tracer [PDF]

, 1977
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core   +1 more source