Results 131 to 140 of about 56,062 (233)

Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]

, 2018
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Asfahani, R, Bellerby, J, Hohenstein, P, Miller-Hodges, EV, Moulding, D, Sampson, RD, Scambler, PJ, Sebire, NJ, Tahoun, MM, Virasami, AK, Waters, AM   +10 more
core  

Lung Biopsy Tract Sealant and Fiducial Marker Based on a Hydrogel/Shape Memory Polymer Foam Composite With Multimodal Contrast

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 4, April 2026.
ABSTRACT Lung tissue biopsies can result in a collapsed lung in the patient via leakage of air (pneumothorax) from an open biopsy tract. To reduce the risk of pneumothorax, clinicians will implant a sealant to prevent leakage of air from the tract.
Matthew A. Jungmann, Donald Bowen, Ethan VanDever, Joseph Alge, Mary P. McDougall, Duncan J. Maitland, Daniel L. Alge   +6 more
wiley   +1 more source

Development of a Novel UPC (Urine Red Blood Cell Distribution, Proteinuria, and Serum Creatinine) Index to Differentiate Glomerular from Nonglomerular Hematuria

Journal of Clinical Laboratory Analysis, Volume 40, Issue 8, April 2026.
The study developed the UPC index by integrating urine red blood cell distribution (URD), urine protein strip, and serum creatinine to enhance the diagnostic accuracy for distinguishing glomerular from nonglomerular hematuria. The UPC index demonstrated superior performance (AUC 0.857) compared to conventional parameters, showing high sensitivity and ...
Hae In Bang, Sun Min Lee, In Hee Lee, A‐Jin Lee, Chang‐Ho Jeon   +4 more
wiley   +1 more source

Outcomes of Kidney Transplants From Donors With Stage 3 Acute Kidney Injury Requiring Dialysis: A National Cohort Study

Clinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Background Whether severe donor acute kidney injury (AKI) requiring dialysis affects posttransplant outcomes remains debated and may influence center‐level acceptance decisions. Methods This retrospective cohort study of United States deceased‐donor kidney transplants (2015–2020) used OPTN data with follow‐up through September 2024.
Amber B. Paulus, Gaurav Gupta, Ahmet Gungor, Alice Toll, Alexandra Lewis, Carlos Martinez, Cassandra McCharen, Wida Cherikh, Bekir Tanriover   +8 more
wiley   +1 more source

Graft Embolization versus Nephrectomy in Patients with Graft Intolerance and Infection: A Retrospective Cohort Study

Clinical Transplantation, Volume 40, Issue 4, April 2026.
ABSTRACT Introduction After graft failure, kidney transplant recipients may develop immunological intolerance to the allograft left in situ. In such cases, surgical removal of the allograft is usually performed, but is associated with substantial morbidity and mortality. A less invasive option is percutaneous embolization of the renal artery.
Mattheüs F. Klaassen, Joost Otterspeer, Madelon van Agteren, Sebastiaan Heidt, Diederik Kimenai, Kay J. Pieterman, Robert C. Minnee, Annelies E. de Weerd   +7 more
wiley   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

CRB2 Facilitates Epithelial Ovarian Cancer Progression by Inducing Polarity Changes via Activation of the Wnt/PCP Signalling Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Ovarian cancer exhibits high molecular heterogeneity and metastatic potential, contributing to its status as a leading cause of gynecologic cancer mortality. Cell polarity is essential in tumorigenesis, yet the role of Crumbs family proteins (CRBs), key regulators of apical–basal polarity, in epithelial ovarian cancer (EOC) remains unclear. In
Chunlin Tao, Shaojing Li, Duohe Sun, Jun Zhou, Yuanping Chen, Rong Zhang, Xiaoge Ni   +6 more
wiley   +1 more source

Optimal management of primary focal segmental glomerulosclerosis in adults

International Journal of Nephrology and Renovascular Disease, 2017
Séverine Beaudreuil,1,2 Hans Kristian Lorenzo,1,2 Michele Elias,1 Erika Nnang Obada,1 Bernard Charpentier,1,2 Antoine Durrbach1,2 1Department of Nephrology Dialysis Transplantation, Paris-Sud University Hospital, Le Kremlin Bicêtre, 2INSERM ...
Beaudreuil S, Lorenzo HK, Elias M, Nnang Obada E, Charpentier B, Durrbach A   +5 more
doaj  

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation

Journal of Diabetes Investigation, Volume 17, Issue 4, Page 576-587, April 2026.
Hesperetin increases cell viability and reduces cell apoptosis, ferroptosis, release of inflammatory cytokines, and oxidative stress of human kidney tubular cells via repressing IGF1R expression. ABSTRACT Background Diabetic nephropathy (DN) accounts for approximately 50% of chronic kidney disease cases.
Yiwen Guo, Fengjiao Zhang, Yu Jin, Menglu Zhu, Zhiqiang Kang   +4 more
wiley   +1 more source

Jefferson Digital Commons quarterly report: October-December 2017 [PDF]

, 2018
This quarterly report includes: Assorted assets added to the JDC in the last quarter Grand Rounds Recordings College Within a College (CWIC) Posters Program of Industrial Design Capstones What people are saying about the ...
Copeland, James, LIBT, Duinkerken, Kelsey, MSI, Kipnis, Dan, MSI   +2 more
core   +1 more source