Results 111 to 120 of about 45,138 (251)
Relationship between KDPI score and glomerulosclerosis.
Comparison of KDPI score and degree of chronic tissue injury (mean glomerulosclerosis percentage) in the results of allograft biopsy performed within three months after KT (rho = 0.368 ...
Jong Hoon Lee (245610) +9 more
core +1 more source
Abstract Background Symmetric dimethylarginine (SDMA) is a biomarker of renal function derived from arginine methylation, unaffected by muscle mass or diet, and increases after only a 25% reduction in renal function, allowing earlier detection of renal dysfunction compared with serum creatinine.
Larissa Ayane do Nascimento Braz +5 more
wiley +1 more source
In 183 male progeny derived from a backcross between the FGS/Kist strain, a new mouse model for focal glomerulosclerosis (FGS) in humans, and the standard normal strain, C57BL/6J, we performed a genome-wide scan for quantitative trait loci (QTLs ...
Eun-Hee KIM +13 more
core +1 more source
Background: Two types of global glomerulosclerosis, glomerular obsolescence and solidification, have been identified. A clinicopathological correlation between these glomerular changes and hypertensive nephrosclerosis has been reported; however ...
Tsutomu Inoue +4 more
doaj +1 more source
ABSTRACT A 7.6‐year‐old boy with hTTP had fever‐induced hemorrhagic rash, MAHA, cerebral infarction, and renal impairment. After plasma therapy, symptoms were partially relieved; 9‐year follow‐up showed regular plasma transfusion was needed, with CKD Stage 3.
Dai Xiaomei +5 more
wiley +1 more source
Linagliptin did not reduce glomerulosclerosis in diabetic mice.
Diabetic mice demonstrated increased glomerulosclerosis, which was improved by telmisartan but not by linagliptin as demonstrated by quantification of glomerulosclerosis by glomerulosclerotic index.
Simon Gross (285318) +4 more
core +1 more source
Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah +5 more
wiley +1 more source
Clinical characteristics of patients with secondary focal segmental glomerulosclerosis (FSGS).
Clinical characteristics of patients with secondary focal segmental glomerulosclerosis (FSGS).
Philip A. Marsden (252499) +11 more
core +1 more source
Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma +9 more
wiley +1 more source
Non-ischemic cardiomyopathy with focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome, accounting for 40% of nephrotic syndrome in adults. FSGS has diverse clinical and morphological features and underlying pathogenesis.
Parminder Kaur +5 more
core +1 more source

