Results 91 to 100 of about 45,138 (251)

Turbulence of glomerular hemodynamics involved in progressive glomerulosclerosis [PDF]

, 2006
There is increasing evidence that changes of glomerular hemodynamics or glomerular growth responses may promote the development of glomerulosclerosis. Major problems retarding research progress include lack of suitable experimental animal models, with ...
Li, B., Morioka, T., Suwa, M., Oite, T., Okada, S., Yao, J., Kawamura, K., Gejyo, F.   +7 more
core   +1 more source

Only IF/TA in the Histological Evaluation of Post-Reperfusion Baseline Biopsies Correlates With Kidney Transplant Outcome

Transplant International
Here, we retrospectively evaluated the informational yield of 338 post-reperfusion kidney transplant biopsies (including 95 living donations) assessed according to BANFF for the histological characteristics interstitial fibrosis and tubular atrophy (IF ...
Quirin Bachmann, Carlos Torrez, Maike Büttner-Herold, Bernhard Haller, Flora Haberfellner, Renate Hausinger, Volker Assfalg, Lutz Renders, Kerstin Amann, Uwe Heemann, Christoph Schmaderer, Stephan Kemmner, Stephan Kemmner   +12 more
doaj   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Adenosine A_2B Receptor Antagonism Interferes with TGF-β Cellular Signaling Through SMAD2/-3 and p65-Nf-κB in Podocytes and Protects from Phenotypical Transformation in Experimental Diabetic Glomerulopathy

Cells
Studies have emphasized alleviating fibrogenesis through interference with adenosine signaling in experimental diabetic nephropathy. We found that the in vivo antagonism of the adenosine A2B receptor (A2BAR) using MRS1754 in diabetic rats impedes the ...
Ignacio Arias, Claudia Jara, Pablo Mendoza-Soto, Yessica Nahuelpán, Claudio Cappelli, Carlos Oyarzún, Diego Carrillo-Beltrán, Claudia Quezada-Monrás, Angelo Torres-Arévalo, Rody San Martín   +9 more
doaj   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

The role of lipids in the pathogenesis of glomerulosclerosis.

, 1989
Most patients with chronic renal impairment develop progressive glomerulosclerosis and eventually require dialysis. The pathogenesis of this process is poorly understood.
Hugh Clive. Rayner (7657910)
core   +5 more sources

Attrition and Delays in Kidney Transplant Evaluation Among People Living With HIV and End‐Stage Renal Disease

Transplant Infectious Disease, EarlyView.
Among people living with HIV and end‐stage renal disease evaluated for kidney transplantation, most progressed successfully through evaluation and were waitlisted once engaged in the process. However, substantial delays occurred across the transplant continuum, with attrition driven primarily by incomplete testing and structural barriers rather than ...
Kyle M. Crawford, Jillian Catalano, Dhriti Shah, Scott Curry, Alexandra G. Mills, Yosra Alkabab, Drew Charles, Courtney E. Harris, Ruth O. Adekunle   +8 more
wiley   +1 more source

Kidney: Ischemic Glomerulosclerosis and Nephrosis.

, 1900
Ischemic glomerulosclerosis and nephrosis ...
MUSC Department of Pathology and Laboratory Medicine
core  

Focal segmental glomerulosclerosis in malignant hypertension [PDF]

, 2017
Objective. Focal segmental glomerulosclerosis (FSG) may occur in primary malignant hypertension (MHT) either as a result of glomerular hyperfi1tration or fibrinoid necrosis (FN), and may contribute to renal dysfunction.
Thomas, JO, Kadiri, S
core  

MYO1E mutations and childhood familial focal segmental glomerulosclerosis

, 2011
BACKGROUND Focal segmental glomerulosclerosis is a kidney disease that is manifested as the nephrotic syndrome. It is often resistant to glucocorticoid therapy and progresses to end-stage renal disease in 50 to 70% of patients.
Andrea Calabria, Fatih Ozaltin, E. Otto, Fabio Macciardi, Paraskevas Iatropoulos, Sevinc Emre, Paola Cassis, Giuseppe Remuzzi, Edgar Otto, P. Cassis, S. Bettoni, M. Delledonne, M. Noris, M. Morigi, I. Abbate, Morigi, Marina, Abbate, Isabella, Ibsirlioglu, Tulin, P. Iatropoulos, T. Ibsirlioglu, Simona Buelli, Carmine Pecoraro, Franz Schaefer, F. Ozaltin, Otto, Edgar, Mira Krendel, R. Maranta, Benigni, Ariela, Piras, Rossella, G. Remuzzi, Isabella Abbate, C. Pecoraro, Maranta, Ramona, Marina Noris, F. Hildebrandt, Friedhelm Hildebrandt, Cassis, Paola, A. Benigni, M. Krendel, Capobianchi, Maria Rosaria, Caterina Mele, F. Schaefer, Delledonne, Massimo, Serena Bettoni, Roberta Donadelli, C. Mele, Iatropoulos, Paraskevas, A. Calabria, Hildebrandt, Friedhelm, Schaefer, Franz, Ramona Maranta, Ariela Benigni, R. Donadelli, S. Emre, Krendel, Mira, Rossella Piras, Emre, Sevinc, Buelli, Simona, R. Piras, Calabria, Andrea, Macciardi, Fabio, Mele, Caterina, Ozaltin, Fatih, Donadelli, Roberta, Maria Rosaria Capobianchi, S. Tomasoni, Remuzzi, Giuseppe, Bettoni, Serena, Susanna Tomasoni, M. R. Capobianchi, Pecoraro, Carmine, S. Buelli, Tomasoni, Susanna, Noris, Marina, Marina Morigi, Massimo Delledonne, F. Macciardi, Tulin Ibsirlioglu   +77 more
core   +1 more source