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An Introduction to Stereology with Applications to the Glomerulus [PDF]
Glomerular Diseases, 2021 <b><i>Background:</i></b> Stereology is the science of inferring quantitative features of 3-dimensional structures from lower dimensional samples of those structures (probes). It is a statistical discipline and therefore may seem intimidating to many potential users.
Kevin V. Lemley
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Biomimetic models of the glomerulus
Nature Reviews Nephrology, 2022 The use of biomimetic models of the glomerulus has the potential to improve our understanding of the pathogenesis of kidney diseases and to enable progress in therapeutics. Current in vitro models comprise organ-on-a-chip, scaffold-based and organoid approaches.
Marta G Valverde +2 more
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Glomerulus Classification and Detection Based on Convolutional Neural Networks
Journal of Imaging, 2018 Glomerulus classification and detection in kidney tissue segments are key processes in nephropathology used for the correct diagnosis of the diseases. In this paper, we deal with the challenge of automating Glomerulus classification and detection from ...
Jaime Gallego +2 more
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The unique synaptic circuitry of specialized olfactory glomeruli in Drosophila melanogaster [PDF]
eLifeIn the Drosophila olfactory system, most odorants are encoded in the antennal lobe in a combinatory way, activating several glomerular circuits. However, odorants of particular ecological role for the fly are encoded through activation of a single ...
Lydia Gruber +7 more
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International Journal of Nephrology and Renovascular Disease, 2022 Kotaro Doi,1 Hiroshi Kimura,2 Yukiko T Matsunaga,1 Teruo Fujii,3 Masaomi Nangaku4 1Institute of Industrial Science, The University of Tokyo, Tokyo, Japan; 2Department of Mechanical Engineering, School of Engineering, Tokai University, Kanagawa, Japan ...
Doi K +4 more
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Identification of Genes Reveals the Mechanism of Cell Ferroptosis in Diabetic Nephropathy
Frontiers in Physiology, 2022 Aims/Introduction: Diabetic nephropathy (DN) is one of the main complications of diabetes. Genomics may reveal the essential pathogenesis of DN. We analyzed datasets to search for key genes to explore pathological mechanisms of DN.Materials and Methods ...
Xian Wang +11 more
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Clinical Journal of the American Society of Nephrology, 2014 The glomerulus, the filtering unit of the kidney, is a unique bundle of capillaries lined by delicate fenestrated endothelia, a complex mesh of proteins that serve as the glomerular basement membrane and specialized visceral epithelial cells that form the slit diaphragms between interdigitating foot processes.
Martin R, Pollak +3 more
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The Glomerulus According to the Mesangium [PDF]
Frontiers in Medicine, 2022 The glomerulus is the functional unit for filtration of blood and formation of primary urine. This intricate structure is composed of the endothelium with its glycocalyx facing the blood, the glomerular basement membrane and the podocytes facing the urinary space of Bowman's capsule. The mesangial cells are the central hub connecting and supporting all
Kerstin Ebefors +2 more
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NMDA Receptor Hypofunction in the Aging-Associated Malfunction of Peripheral Tissue
Frontiers in Physiology, 2021 Glutamatergic transmission through NMDA receptors (NMDARs) is important for the function of peripheral tissues. In the bone, NMDARs and its co-agonist, D-serine participate in all the phases of the remodeling.
Angélica Rivera-Villaseñor +7 more
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