Results 41 to 50 of about 48,150 (297)
Illustrates the complex 3D arrangement of the glomerulus and microfibers in the WT.
, 2023 Illustrates the complex 3D arrangement of the glomerulus and microfibers in the WT.
Dieter P. Reinhardt (15440641) +8 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Spectrins and ankyrin distribution in the glomerulus.
, 2016 ImmunoEM micrographs of spectrin and ankyrin in the glomerulus. Spectrin βΙΙ staining was largely confined to endothelial cells. Spectrin βΙΙΙ was present in both endothelial cells (arrow head) and podocytes (arrow).
Michael C. Stankewich (842238) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Optical coherence tomography of the living human kidney [PDF]
Journal of Innovative Optical Health Sciences, 2014 Acute tubular necrosis (ATN) induced by ischemia is the most common insult to donor kidneys destined for transplantation. ATN results from swelling and subsequent damage to cells lining the kidney tubules.
Peter M. Andrews +6 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Evolutionary Origin of the Proepicardium
Journal of Developmental Biology, 2013 The embryonic epicardium and the cardiac mesenchyme derived from it are critical to heart development. The embryonic epicardium arises from an extracardiac progenitor tissue called the proepicardium, a proliferation of coelomic cells located at the limit
Elena Cano +2 more
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
Journal of PharmacopunctureBackground: Diabetic nephropathy (DN) is one of the major complications of chronic hyperglycaemia affecting normal kidney functioning. The ayurvedic medicine curcumin (CUR) is pharmaceutically accepted for its vast biological effects.Objectives: The ...
Asmita Samadder +8 more
doaj +1 more source
KLASIFIKASI GLOMERULUS BERDASARKAN CITRA HISTOLOGI GINJAL MENGGUNAKAN BACKPROPAGATION NEURAL NETWORK
, 2021 Citra histologi merupakan salah satu alat yang digunakan oleh nephropathology untuk melakukan diagnosis terkait kondisi ginjal pasien. Glomerulus adalah bagian ginjal yang berfungsi untuk menyaring zat sisa dan membuang cairan serta elektrolit berlebih ...
Kurniastuti, Ima +2 more
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