Results 11 to 20 of about 48,150 (297)

Biomimetic models of the glomerulus [PDF]

Nature Reviews Nephrology, 2022
The use of biomimetic models of the glomerulus has the potential to improve our understanding of the pathogenesis of kidney diseases and to enable progress in therapeutics. Current in vitro models comprise organ-on-a-chip, scaffold-based and organoid approaches.
Marta G. Valverde, Luis S. Mille, Kianti P. Figler, Ernesto Cervantes, Vanessa Y. Li, Joseph V. Bonventre, Rosalinde Masereeuw, Yu Shrike Zhang   +7 more
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A comparative analysis of glomerulus development in the pronephros of medaka and zebrafish.

PLoS ONE, 2012
The glomerulus of the vertebrate kidney links the vasculature to the excretory system and produces the primary urine. It is a component of every single nephron in the complex mammalian metanephros and also in the primitive pronephros of fish and ...
Koichiro Ichimura, Ekaterina Bubenshchikova, Rebecca Powell, Yayoi Fukuyo, Tomomi Nakamura, Uyen Tran, Shoji Oda, Minoru Tanaka, Oliver Wessely, Hidetake Kurihara, Tatsuo Sakai, Tomoko Obara   +11 more
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The Glomerulus [PDF]

Clinical Journal of the American Society of Nephrology, 2014
The glomerulus, the filtering unit of the kidney, is a unique bundle of capillaries lined by delicate fenestrated endothelia, a complex mesh of proteins that serve as the glomerular basement membrane and specialized visceral epithelial cells that form the slit diaphragms between interdigitating foot processes.
Martin R, Pollak, Susan E, Quaggin, Melanie P, Hoenig, Lance D, Dworkin   +3 more
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The Glomerulus According to the Mesangium [PDF]

Frontiers in Medicine, 2022
The glomerulus is the functional unit for filtration of blood and formation of primary urine. This intricate structure is composed of the endothelium with its glycocalyx facing the blood, the glomerular basement membrane and the podocytes facing the urinary space of Bowman's capsule. The mesangial cells are the central hub connecting and supporting all
Kerstin Ebefors, Lovisa Bergwall, Jenny Nyström   +2 more
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MicroRNAs and the glomerulus [PDF]

Experimental Cell Research, 2012
MicroRNAs (miRNAs) are short non-coding RNAs regulating gene expression at the post-transcriptional level by blocking translation or promoting cleavage of their target mRNAs. Increasing evidence shows that miRNAs play central roles in gene transcription, signal transduction and pathogenesis of human diseases.
Mitsuo, Kato, Jung Tak, Park, Rama, Natarajan   +2 more
openaire   +3 more sources

Histology of glomerulus.

, 2023
A. Scheme of the kidney region in cross-section. B. Histological analysis (PAS staining) at low magnification (B) and high magnification (C) of the renal cortex, yellow and black dotted lines delimit the normal glomerulus and reduced glomerulus ...
Dieter P. Reinhardt (15440641), Keith M. Meek (10172678), Rodrigo Barbosa de Souza (7866368), Orestes Foresto-Neto (8432751), Lygia V. Pereira (7866386), Luara Lucena Cassiano (15440638), Renan Barbosa Lemes (10469425), Philip N. Lewis (15440644), Ivan Hong Jun Koh (6156680)   +8 more
core   +1 more source

Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset [PDF]

, 2010
Glomerular diseases account for the majority of cases with chronic renal failure. Several genes have been identified with key relevance for glomerular function.
Clemens D Cohen, Ilka Edenhofer, Felix Eichinger, Rastaldi, Maria P., Maja T. Lindenmeyer, Hans-Joachim Anders, Lindenmeyer, M T, Cohen Clemens D., Eichinger, Felix, Eichinger Felix, Kretzler, Matthias, Mattinzoli, D, Deborah Mattinzoli, Maja T Lindenmeyer, Maria P. Rastaldi, Cohen, Clemens D., Kretzler, M, Sen, Kontheari, Rastaldi Maria P., Matthias Kretzler, Edenhofer, I, Lindenmeyer, Maja T., Anders Hans-Joachim, Clemens D. Cohen, Cohen, C D, Maria P Rastaldi, Mattinzoli Deborah, Mattinzoli, Deborah, Anders, Hans-Joachim, Sen Kontheari, Kretzler Matthias, Edenhofer, Ilka, Kontheari Sen, Lindenmeyer Maja T., Rastaldi, M P, Edenhofer Ilka, Eichinger, F, Sen, K, Mattinzoli D, Anders HJ, Eichinger F, Lindenmeyer MT, Cohen CD, Sen K, Kretzler M, Rastaldi MP, Edenhofer I   +46 more
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Prenatal glomerular changes during development of human foetal kidney

National Journal of Clinical Anatomy, 2016
Background and aims: The cortical glomerulus shows many developmental changes during fetogenesis. Normal histology of the fetal glomerulus at various stages of development was studied to get insight into the morphology of fetal glomerulus.
Roli Joshi, Deepa Deopa, D N Sinha, A K Singh   +3 more
doaj   +1 more source

Histomorphometric Analysis of Chick Embryo Kidneys on Exposure to 1800 MHz and 2100 MHz Radiofrequency Radiation Emitted from Cell Phone [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: With its sophisticated and multifunctional features, the cell phone has become an integral part of human life. Scientific reports are still inconclusive, regarding the possible ill effects of Radiofrequency Radiation (RFR) emitted from ...
Mary Hydrina Dsilva, Rijied Thompson Swer, Jayaraman Anbalagan   +2 more
doaj   +1 more source

Kidney-on-a-Chip: Mechanical Stimulation and Sensor Integration

Sensors, 2022
Bioengineered in vitro models of the kidney offer unprecedented opportunities to better mimic the in vivo microenvironment. Kidney-on-a-chip technology reproduces 2D or 3D features which can replicate features of the tissue architecture, composition, and
Dan Wang, Matthew Gust, Nicholas Ferrell
doaj   +1 more source