Results 51 to 60 of about 68,068 (346)

Fine particulate matter (PM2.5) induces microRNA-192–5p causing glomerular damage

Ecotoxicology and Environmental Safety
An association between air pollution and the incidence of membranous glomerulonephritis (MGN) has been shown in epidemiological studies. However, the causality of this relationship and data on potential pathomechanisms are still missing.
Melina Yarbakht, George Sarau, Yanyi Xu, Xinyi Fang, Zeynab Mirzaei, René Krüger, Yalan Xiao, Arslan Usman, Christoph Daniel, Mario Schiffer, Silke Christiansen, Janina Müller-Deile   +11 more
doaj   +1 more source

A comparative analysis of glomerulus development in the pronephros of medaka and zebrafish.

PLoS ONE, 2012
The glomerulus of the vertebrate kidney links the vasculature to the excretory system and produces the primary urine. It is a component of every single nephron in the complex mammalian metanephros and also in the primitive pronephros of fish and ...
Koichiro Ichimura, Ekaterina Bubenshchikova, Rebecca Powell, Yayoi Fukuyo, Tomomi Nakamura, Uyen Tran, Shoji Oda, Minoru Tanaka, Oliver Wessely, Hidetake Kurihara, Tatsuo Sakai, Tomoko Obara   +11 more
doaj   +1 more source

Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney

Frontiers in Medicine, 2020
Molecular assessments at the single cell level can accelerate biological research by providing detailed assessments of cellular organization and tissue heterogeneity in both disease and health.
Tara K. Sigdel, Paul D. Piehowski, Sudeshna Roy, Juliane Liberto, Joshua R. Hansen, Adam C. Swensen, Rui Zhao, Ying Zhu, Priyanka Rashmi, Andrew Schroeder, Izabella Damm, Swastika Sur, Jinghui Luo, Yingbao Yang, Wei-Jun Qian, Minnie M. Sarwal, The Kidney Precision Medicine Project (KPMP) Consortium   +16 more
doaj   +1 more source

Iterative annotation to ease neural network training: Specialized machine learning in medical image analysis [PDF]

, 2018
Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks.
Ginley, Brandon, Govind, Darshana, Jain, Sanjay, Jen, Kuang-Yu, LaViolette, Peter S., Lutnick, Brendon, McGarry, Sean D., Sarder, Pinaki, Tomaszewski, John E., Yacoub, Rabi   +9 more
core   +2 more sources

The UW solution for canine kidney preservation: Its specific effect on renal hemodynamics and microvasculature [PDF]

, 1989
The preservation effects of UW solution on renal hemodynamics and microvascular systems were studied in canine kidney autografts. In 72-hr UW-preserved kidneys, the microvessels of both cortex and medulla were completely visualized with silicon rubber ...
Furukawa, H, Imventarza, O, Oguma, S, Oks, A, Starzl, TE, Todo, S, Ueda, Y, Wu, YM   +7 more
core   +1 more source

Research Progress of Drug Delivery Systems Targeting the Kidneys

Pharmaceuticals
Chronic kidney disease (CKD) affects more than 10% of the global population, and its incidence is increasing, partially due to an increase in the prevalence of disease risk factors.
Li-Feng Huang, Qiao-Ru Ye, Xiao-Cui Chen, Xiao-Rong Huang, Qiao-Fei Zhang, Chun-Yu Wu, Hua-Feng Liu, Chen Yang   +7 more
doaj   +1 more source

Pemberian Ekstrak Etanol Daun Salam untuk Menurunkan Ekspresi TGF-β Podosit Glomerulus Tikus Sprague dawley Diabetes Melitus [PDF]

, 2014
Latar Belakang : Diabetes melitus merupakan kelompok sindrom metabolik yang dapat mengakibatkan peningkatan growth factor pada glomerulus, salah satunya yaitu ekspresi TGF-β di podosit.
rumaolat, wiwi
core  

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney [PDF]

, 2015
BACKGROUND: The role of cyclooxygenase(COX)-1 and COX-2 in the saluretic and renin-angiotensin responses to loop diuretics in the cat is unknown. We propose in vivo characterisation of isoform roles in a furosemide model by administering non-steroidal ...
A Hayes, B Mann, B Rose, B Rose, B Rose, CM Hao, DA Heller, DO Stichtenoth, F Catella-Lawson, F Nantel, G Giovanni, H Syme, H. Syme, J Hippisley-Cox, J Peti-Peterdi, J. Elliott, J. N. King, JA Jakobsen, K Schumacher, K. Smith, KA Kirchner, KL Therland, KN Khan, KN Khan, L Pelligand, L Pelligand, L. Pelligand, M Komhoff, M Meskell, M Sabbatini, N. Suemanotham, P. Lees, PA Friedman, RC Harris, RC Harris, RE Jepson, S Yu, V Campean, V Sreenivasan, VB Schmid, W. Seewald, WA Corsini, XR He   +42 more
core   +3 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Optical coherence tomography of the living human kidney [PDF]

Journal of Innovative Optical Health Sciences, 2014
Acute tubular necrosis (ATN) induced by ischemia is the most common insult to donor kidneys destined for transplantation. ATN results from swelling and subsequent damage to cells lining the kidney tubules.
Peter M. Andrews, Hsing-Wen Wang, Jeremiah Wierwille, Wei Gong, Jennifer Verbesey, Matthew Cooper, Yu Chen   +6 more
doaj   +1 more source