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Glucagon-like Peptide-1 Receptor Agonists in Heart Failure: Mechanisms, Evidence and Identifying Optimal Candidates. [PDF]

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Abdelhamid M, Abdrabou MM, Faris E, El Kafas S, Hosny M, Hassan A.   +5 more
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Metabolic Messengers: glucagon-like peptide 1

Nature Metabolism, 2021
Glucagon like peptide-1 (GLP-1), a peptide hormone from the intestinal tract, plays a central role in the coordination of postprandial glucose homeostasis through actions on insulin secretion, food intake and gut motility. GLP-1 forms the basis for a variety of current drugs for the treatment of type 2 diabetes and obesity, as well as new agents ...
Fiona M. Gribble, Frank Reimann
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Glucagon-like peptide-1 agonists

BMJ, 2012
Cannot be recommended strictly for weight reduction until their benefits and risks are ...
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Glucagon Like Peptide-1 and Atherosclerosis

Cardiovascular & Hematological Agents in Medicinal Chemistry, 2012
Patients with type 2 diabetes mellitus are at high risk for developing cardiovascular diseases. Traditional medicines for type 2 diabetes, such as sulfonylureas, pioglitazone, and insulin have glucose lowering effects; however, they also increase the frequency of hypoglycemia and/or body weight and thus may cancel out the benefits of glucose lowering ...
Tomoya, Mita, Hirotaka, Watada
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Glucagon-like peptide-1 and glucagon-like peptide-2

Best Practice & Research Clinical Endocrinology & Metabolism, 2004
The glucagon-like peptides (glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2)) are released from enteroendocrine cells in response to nutrient ingestion. GLP-1 enhances glucose-stimulated insulin secretion and inhibits glucagon secretion, gastric emptying and feeding. GLP-1 also has proliferative, neogenic and antiapoptotic effects on
Laurie L. Baggio, Daniel J. Drucker
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Glucagon-like peptide-1 receptor

Current Biology
Michael Krashes discusses glucagon-like peptide-1 receptors, their physiological role in glucose metabolism and the mode of action of their agonists that are used to treat obesity and were later shown to promote weight loss.
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