Results 111 to 120 of about 214,982 (356)

Comment. Is incretin-based therapy ready for the care of hospitalized patients with type 2 diabetes? [PDF]

, 2014
Adam M.
A. M. Deane, Deane, Deane, Deane, M. Horowitz, Schwartz, Umpierrez   +6 more
core   +1 more source

Self‐Administered Taste Testing Without Water: Normative Data for the 53‐Item Waterless Empirical Taste Test (WETT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background According to the National Health and Nutrition Examination Survey (NHANES), more than 20 million Americans suffer from chronic taste problems. Unfortunately, quantitative testing is rarely performed, self‐reports are inaccurate, and “taste” is often confused with olfaction‐dependent flavors.
Richard L. Doty, Ryan Sharetts, Shima T. Moein   +2 more
wiley   +1 more source

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]

, 1979
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM, Rindler, MJ, Saier, MH, Shaffer, L   +3 more
core  

Strategies for optimization of hypoglycemia rat models

Animal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher, Eason Kong Qi Zheng, Rayneshia Elaura Raymond, Ye Zhen Jie, Christina Gertrude Yap   +4 more
wiley   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

Annals of Neurology, EarlyView.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam, Christine Girges, Martin Wiegand, Claudia Ismail, Alexandra Lameirinhas, Alison Yarnall, Cameron Kirk, Silvia Del‐Din, Lynn Rochester, Christopher Kobylecki, Gareth Ambler, Simon Skene, Henry Houlden, Viorica Chelban, Amanda Heslegrave, Wendy Phillips, Alan Whone, Niall Quinn, Christian Lambert, Charlotte Dore, Huw R. Morris, Mathew H. Horrocks, Ji Eun Lee, Judi O'Shaughnessy, Yazhou Li, Nigel H. Greig, Sonia Gandhi, Vincenzo Libri, Dilan Athauda, Tom Foltynie   +29 more
wiley   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

ANALYSIS OF THE BLOOD SUGAR RESPONSE OF OBESE-HYPERGLYCEMIC MICE AND NORMAL MICE TO HORMONES: INSULIN, GLUCAGON, AND EPINEPHRINE1 [PDF]

, 1956
Kenneth H. Shull, Jean Mayer, Demetra J. Silides   +2 more
openalex   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Glycemic and Metabolic Effects of Two Long Bouts of Moderate-Intensity Exercise in Men with Normal Glucose Tolerance or Type 2 Diabetes

Frontiers in Endocrinology, 2017
BackgroundThe glycemic and insulinemic responses following 30–60 min of exercise have been extensively studied, and a dose–response has been proposed between exercise duration, or volume, and improvements in glucose tolerance or insulin sensitivity ...
Saeed Reza Eshghi, Saeed Reza Eshghi, Kevin Fletcher, Kevin Fletcher, Étienne Myette-Côté, Étienne Myette-Côté, Cody Durrer, Raniah Q. Gabr, Jonathan P. Little, Peter Senior, Peter Senior, Craig Steinback, Craig Steinback, Margie H. Davenport, Margie H. Davenport, Gordon J. Bell, Gordon J. Bell, Dion R. Brocks, Normand G. Boulé, Normand G. Boulé   +19 more
doaj   +1 more source