Results 11 to 20 of about 131,242 (269)

13C MRS Studies of the Control of Hepatic Glycogen Metabolism at High Magnetic Fields

open access: yesFrontiers in Physics, 2017
Introduction: Glycogen is the primary intracellular storage form of carbohydrates. In contrast to most tissues where stored glycogen can only supply the local tissue with energy, hepatic glycogen is mobilized and released into the blood to maintain ...
Corin O. Miller   +6 more
doaj   +1 more source

Somatostatin receptors in congenital hyperinsulinism: Biology to bedside

open access: yesFrontiers in Endocrinology, 2022
Congenital hyperinsulinism (CHI), although a rare disease, is an important cause of severe hypoglycemia in early infancy and childhood, causing preventable morbidity and mortality.
Mirjam E. van Albada   +4 more
doaj   +1 more source

Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation

open access: yesFrontiers in Physiology, 2018
High-fat-diet (HFD) feeding induces adipose dysfunction. This study aims to explore whether the Traditional Chinese Medical prescription Er-Miao-Fang could ameliorate adipose dysfunction and prevent hepatic glucose output.
Wenjun Zhao   +5 more
doaj   +1 more source

The VIP/VPAC1R Pathway Regulates Energy and Glucose Homeostasis by Modulating GLP-1, Glucagon, Leptin and PYY Levels in Mice

open access: yesBiology, 2022
Vasoactive Intestinal Peptide binds with high affinity to VPAC1R and VPAC2R, thus regulating key physiologic functions. Previously, we documented in VIP−/− mice a leaner body phenotype and altered metabolic hormones.
Daniel Sanford   +7 more
doaj   +1 more source

Enhancing endogenous levels of GLP1 dampens acute olanzapine induced perturbations in lipid and glucose metabolism

open access: yesFrontiers in Pharmacology, 2023
Olanzapine is a second-generation antipsychotic (SGA) used in the treatment of schizophrenia and several on- and off-label conditions. While effective in reducing psychoses, acute olanzapine treatment causes rapid hyperglycemia, insulin resistance, and ...
Kyle D. Medak   +11 more
doaj   +1 more source

Partners for life

open access: yeseLife, 2016
The hormones insulin and glucagon both play important roles in the development of diabetes.
Lena Eliasson, Anna Wendt
doaj   +1 more source

Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2016
Introduction: In healthy carriers of the T allele of the transcription factor 7-like 2 (TCF7L2), fasting plasma glucagon concentrations are lower compared with those with the C allele.
Peter L Kristensen   +9 more
doaj   +1 more source

Effects of Exercise Training and IL-6 Receptor Blockade on Gastric Emptying and GLP-1 Secretion in Obese Humans: Secondary Analyses From a Double Blind Randomized Clinical Trial

open access: yesFrontiers in Physiology, 2019
BackgroundInterleukin-6 (IL-6) is released from skeletal muscle during exercise and systemic IL-6 levels therefore increase acutely in response to a single bout of exercise.
Louise Lang Lehrskov   +22 more
doaj   +1 more source

Epinephrine binding and the selective restoration of adenylate cyclase activity in fat-fed rats

open access: yesJournal of Lipid Research, 1973
Fat feeding results in a progressive loss of epinephrine- and glucagon-stimulated adenylate cyclase activity in adipocyte plasma membrane sacs (ghosts).
Robert R. Gorman   +2 more
doaj   +1 more source

Entero-insular axis in children with simple obesity [PDF]

open access: yesPediatric Endocrinology, Diabetes and Metabolism, 2009
Introduction: The entero-insular axis plays an important role in generation ofsatiety signal. Thus, disturbances in this axis can influence the path to a simple obesity.
Jerzy Starzyk   +2 more
doaj  

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