A New Era in Obesity Treatment: The Evolution of Antiobesity Medications (AOMs) Based on Clinical Trials. [PDF]
Liu D, Chen Y.
europepmc +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong+4 more
wiley +1 more source
Survodutide: a novel peptide for treatment of obesity and metabolic diseases. [PDF]
Vinton TY.
europepmc +1 more source
Effects of glucagon and insulin on cytoplasmic protein phosphorylation in hepatocytes
Joseph Avruch+3 more
openalex +1 more source
Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz+5 more
wiley +1 more source
Glucagon-like peptide 1 (GLP-1) receptor agonists' use during pregnancy: Safety data from regulatory clinical trials. [PDF]
Parker CH+3 more
europepmc +1 more source
Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients
ABSTRACT Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiology, clinically resembling pancreatic cancer, yet uniquely responsive to steroid treatment.
Vladyslav Dovhalyuk+5 more
wiley +1 more source
Activin B improves glucose metabolism via induction of Fgf21 and hepatic glucagon resistance. [PDF]
Kobayashi N+17 more
europepmc +1 more source