Results 21 to 30 of about 214,982 (356)
The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes
Objective: Glucagon and amino acids may be regulated in a feedback loop called the liver-alpha-cell axis with alanine or glutamine as suggested signal molecules.
Julia Otten+7 more
doaj +1 more source
Evidence that host size determines liver size: Studies in dogs receiving orthotopic liver transplants [PDF]
Orthotopic liver transplantation was performed in two groups of dogs; Group I animals consisted of large dogs that served as recipients of livers obtained from smaller dogs while Group II animals consisted of dogs that received liver from donor dogs of ...
Bucher+28 more
core +1 more source
New uses and formulations of glucagon for hypoglycaemia
Hypoglycaemia is the more frequent complication of insulin therapy and the main barrier to tight glycaemic control. Injectable glucagon and oral intake of carbohydrates are the recommended treatments for severe and non-severe hypoglycaemia episodes ...
Pilar I Beato-Víbora+1 more
doaj +1 more source
Circulating free fatty acids, insulin, and glucose during chemical stimulation of hypothalamus in rats [PDF]
The aim of this study was to investigate plasma free fatty acids (FFA), insulin, and blood glucose during chemical stimulation of the lateral and ventromedial hypothalamic areas (LHA and VMH) in rats.
Damsma, G.,+3 more
core +1 more source
Objective:Hypoglycemia is a common acute complication of type 1 diabetes (T1D), which may cause seizure, loss of consciousness, and temporary motor or sensory impairment.
Serra Muradoğlu+4 more
doaj +1 more source
Striking the Balance: GLP-1/Glucagon Co-Agonism as a Treatment Strategy for Obesity
Obesity and Type 2 diabetes represent global health challenges, and there is an unmet need for long-lasting and effective pharmacotherapies. Although long-acting glucagon-like peptide-1 (GLP-1) analogues are now in routine use for diabetes and are now ...
David C. D. Hope+2 more
doaj +1 more source
Cyclic AMP signalling in pancreatic islets [PDF]
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian+2 more
core +1 more source
Glycemia Regulation: From Feedback Loops to Organizational Closure. [PDF]
Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range ...
Bich, Leonardo+2 more
core +4 more sources
The associations of incretin hormone concentration with gestational diabetes mellitus
Background: Enteropancreatic hormonal system disorder is a possible reason for β-cell dysfunction and carbohydrate metabolism disorder among pregnant women. However, no information is available about the state of enteroinsulin hormones [glucagon, glucose-
Tatiana V. Saprina+7 more
doaj +1 more source
Glucagon Antibodies and Their Use for Immunoassay for Glucagon.
SummaryNon-precipitating antibodies to glucagon have been produced in rabbits and detected by both Berson-Yalow and Skom-Talmadge technics.
Mary Sue McCall+5 more
openaire +3 more sources