Results 21 to 30 of about 222,938 (359)

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

open access: yes, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu   +4 more
core   +3 more sources

Glycemia Regulation: From Feedback Loops to Organizational Closure. [PDF]

open access: yes, 2020
Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range ...
Bich, Leonardo   +2 more
core   +4 more sources

Cyclic AMP signalling in pancreatic islets [PDF]

open access: yes, 2010
Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian   +2 more
core   +1 more source

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

open access: yes, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC   +5 more
core   +2 more sources

Liver regeneration in dogs: Morphologic and chemical changes [PDF]

open access: yes, 1978
Forty-four percent and 72% hepatectomy were carried out in dogs and the animals were sacrificed for biochemical and pathologic studies from 0.5 to 6 days later.
Antonio Francavilla   +34 more
core   +1 more source

New uses and formulations of glucagon for hypoglycaemia

open access: yesDrugs in Context, 2019
Hypoglycaemia is the more frequent complication of insulin therapy and the main barrier to tight glycaemic control. Injectable glucagon and oral intake of carbohydrates are the recommended treatments for severe and non-severe hypoglycaemia episodes ...
Pilar I Beato-Víbora   +1 more
doaj   +1 more source

Glucagon Antibodies and Their Use for Immunoassay for Glucagon.

open access: yesExperimental Biology and Medicine, 1959
SummaryNon-precipitating antibodies to glucagon have been produced in rabbits and detected by both Berson-Yalow and Skom-Talmadge technics.
Mary Sue McCall   +5 more
openaire   +3 more sources

Evidence that host size determines liver size: Studies in dogs receiving orthotopic liver transplants [PDF]

open access: yes, 1987
Orthotopic liver transplantation was performed in two groups of dogs; Group I animals consisted of large dogs that served as recipients of livers obtained from smaller dogs while Group II animals consisted of dogs that received liver from donor dogs of ...
Bucher   +28 more
core   +1 more source

Striking the Balance: GLP-1/Glucagon Co-Agonism as a Treatment Strategy for Obesity

open access: yesFrontiers in Endocrinology, 2021
Obesity and Type 2 diabetes represent global health challenges, and there is an unmet need for long-lasting and effective pharmacotherapies. Although long-acting glucagon-like peptide-1 (GLP-1) analogues are now in routine use for diabetes and are now ...
David C. D. Hope   +2 more
doaj   +1 more source

An Evaluation of Glucagon Injection Anxiety and Its Association with the Fear of Hypoglycemia among the Parents of Children with Type 1 Diabetes

open access: yesJCRPE, 2021
Objective:Hypoglycemia is a common acute complication of type 1 diabetes (T1D), which may cause seizure, loss of consciousness, and temporary motor or sensory impairment.
Serra Muradoğlu   +4 more
doaj   +1 more source

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