Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]
Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J.+8 more
core
Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise+6 more
core +1 more source
Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]
The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Alleaume, Céline+4 more
core +1 more source
Entero-insular axis in children with simple obesity [PDF]
Introduction: The entero-insular axis plays an important role in generation ofsatiety signal. Thus, disturbances in this axis can influence the path to a simple obesity.
Jerzy Starzyk+2 more
doaj
Hypoglycaemic crisis induced by non-islet cell tumours in two dogs
Two dogs were admitted for the diagnosis and treatment of neoplasia (a hepatic and a mammary tumour, respectively), lethargy, quadriparesis and abnormal mentation with hypoglycaemia.
Hakhyun Kim+3 more
doaj +1 more source
Glucagon Receptor Signaling and Lipid Metabolism
Glucagon is secreted from the pancreatic alpha cells upon hypoglycemia and stimulates hepatic glucose production. Type 2 diabetes is associated with dysregulated glucagon secretion, and increased glucagon concentrations contribute to the diabetic ...
Katrine D. Galsgaard+11 more
doaj +1 more source
THE PHYSIOLOGIC SIGNIFICANCE OF THE SECRETION OF ENDOGENOUS INSULIN INTO THE PORTAL CIRCULATION. I. COMPARISON OF THE EFFECTS OF GLUCAGON-FREE INSULIN ADMINISTERED VIA THE PORTAL VEIN AND VIA A PERIPHERAL VEIN ON THE MAGNITUDE OF HYPOGLYCEMIA AND PERIPHERAL GLUCOSE UTILIZATION1 [PDF]
Leonard L. Madison, Roger H. Unger
openalex +1 more source
THE INTERACTION OF GLUCAGON AND INSULIN ON BLOOD GLUCOSE [PDF]
Harold Elrick+3 more
openalex +1 more source
Why Glucagon Matters for Hypoglycemia and Physical Activity in Individuals With Type 1 Diabetes
Sheri R. Colberg
doaj +1 more source
Changing paradigms in type 2 diabetes mellitus
Diabetes mellitus has been increasing in prevalence and imposes serious economic burdens on both the developed as well as the developing world. Understanding pathobiological underpinning of chronic progressive disease like diabetes is an imperative that ...
Romesh Khardori
doaj +1 more source