Results 51 to 60 of about 403,504 (246)
Frontiers in Neuroscience, 2023 ObjectiveTo investigate the clinical efficacy and prognostic factors of transnasal endoscopic optic decompression in the treatment of traumatic optic neuropathy (TON).MethodsA retrospective analysis was performed on 13 TON patients in The Seventh ...
Xiang Tu +7 more
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Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay. [PDF]
, 2017 BackgroundGlucocorticoid receptor (GR) activity plays a role in many aspects of human physiology and may play a crucial role in chemotherapy resistance in a wide variety of solid tumors.
Block, Thaddeus S +4 more
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Stress, Allostatic Load, and Psychosis: One Step Forward in Research But Where to Go Next?
Frontiers in Psychiatry, 2020 Stress exposure leads to the activation of several biological mechanisms that have been termed allostasis. These processes enable adaptation to novel situations; however; their prolonged activation exerts systemic and detrimental effects called the ...
Błażej Misiak
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A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]
, 2017 Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho +5 more
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Rheumatology and TherapyIntroduction Glucocorticoids are commonly used to treat immunoglobulin G4-related disease (IgG4-RD), but there is limited real-world evidence describing glucocorticoid-related toxicities in this population.
Zachary S. Wallace +7 more
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Trials, 2011 Background Traumatic brain injury (TBI) is a main cause of severe prolonged disability of young patients. Hospital acquired pneumonia (HAP) add to the morbidity and mortality of traumatic brain-injured patients. In one study, hydrocortisone for treatment
Asehnoune Karim +3 more
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Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release [PDF]
, 2007 We investigated the effect of the glucocorticoid receptor (GR) antagonist Org 34850 on fast and delayed inhibition of corticosterone secretion in response to the synthetic glucocorticoid methylprednisolone (MPL).
Craighead, Mark +7 more
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The Effect of Chronic Glucocorticoid Exposure on Brown Adipose Tissue in Cushing’s Disease
Haseki Tıp Bülteni, 2021 Aim:In this study, we aimed to evaluate the levels of brown adipose tissue markers uncoupling protein-1 (UCP-1), irisin, bone morphogenetic protein-7 (BMP-7) and PR-Domain Zinc Finger Protein-16 (PRDM-16) in Cushing’s disease (CH) with hypercortisolism ...
Alev Selek +7 more
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HIF-1α Regulates Glucocorticoid-Induced Osteoporosis Through PDK1/AKT/mTOR Signaling Pathway
Frontiers in Endocrinology, 2020 Long-term and high dose glucocorticoid treatment can cause decreased viability and function of osteoblasts, which leads to osteoporosis and osteonecrosis. In this study, we investigated the role and mechanism of action of HIF-1α in glucocorticoid-induced
Wen-Ning Xu +4 more
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気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]
, 2002 Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo +8 more
core +1 more source