Results 81 to 90 of about 460,157 (392)

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra, Anne-Margriet Huisman, Ans C.M. Oostveen, Ben A.C. Dijkmans, Chris E.D. de Laet, de Nijs RN, Erik Buskens, George A.W. Bruyn, Johannes W.G. Jacobs, Johannes W.J. Bijlsma, Michel BA, Piet P.M.M. Geusens, Roland F.J. Laan, Ron N.J. de Nijs, Willem F. Lems   +14 more
core   +4 more sources

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri, Manuel Meraz, Hamraz Mokri, Sajesh K Veettil, Karn Wijarnpreecha, Naomi Schlesinger, Arthur Kavanaugh, Nathorn Chaiyakunapruk   +7 more
wiley   +1 more source

Dexamethasone Administration During Late Gestation Has No Major Impact on Lipid Metabolism, but Reduces Newborn Survival Rate in Wistar Rats

Frontiers in Physiology, 2018
A rise in plasma triacylglycerol levels is a common physiological occurrence during late gestation and excess of glucocorticoids (GCs) has been shown to impair lipid metabolism.
Katia Motta, Patricia R. L. Gomes, Paola M. Sulis, Silvana Bordin, Alex Rafacho   +4 more
doaj   +1 more source

Effect of adrenocorticotropic hormone infusion on circulating sclerostin levels

Endocrine Connections, 2021
Glucocorticoid use is the most common cause of secondary osteoporosis. Poor skeletal health related to glucocorticoid use is thought to involve inhibition of the Wnt/β-catenin signaling pathway, a key pathway in osteoblastogenesis.
Sarah Zaheer, Kayla Meyer, Rebecca Easly, Omar Bayomy, Janet Leung, Andrew W Koefoed, Mahyar Heydarpour, Roy Freeman, Gail K Adler   +8 more
doaj   +1 more source

Glucocorticoid-induced osteoporosis

RMD Open, 2015
Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the first cause in young people. Bone loss and increased rate of fractures occur early after the initiation of corticosteroid therapy, and are then related to ...
K. Briot, C. Roux
semanticscholar   +1 more source

The effect of therapeutic glucocorticoids on the adrenal response in a randomized controlled trial in patients with rheumatoid arthritis [PDF]

, 2005
Objective. To measure the effect of low-dose systemic glucocorticoid treatment on the adrenal response to adrenocorticotropic hormone (ACTH) in patients with rheumatoid arthritis (RA). Methods.
Arnett, Buttgereit, Byyny, Chamberlain, Chikenza, Clark, Crofford, Edsbacker, Edsbacker, Greig, Gudbjornsson, Harbuz, Harbuz, Hench, Henzen, Hicklin, Hsu, Jasani, Kanik, Kirwan, Kirwan, Neeck, Rutgeerts, Schlaghecke, Shuster, Spiegel, Treadwell, Wood   +27 more
core   +1 more source

Ageism in Rheumatology: The Health Care Professional's Perspective

Arthritis Care &Research, EarlyView.
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith, Pooja M. Achanta, Jiha Lee, Namrata Singh, Una E. Makris   +4 more
wiley   +1 more source

Glucocorticoid-induced delayed fracture healing and impaired bone biomechanical properties in mice

Clinical Interventions in Aging, 2018
Yan-zhi Liu,1,2 Mohammed P Akhter,3 Xiang Gao,4 Xiao-yan Wang,2 Xiao-bei Wang,2 Gang Zhao,2 Xin Wei,2 Hao-jun Wu,4 Hang Chen,4 Dong Wang,2 Liao Cui1 1Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University ...
Liu YZ, Akhter MP, Gao X, Wang XY, Wang XB, Zhao G, Wei X, Wu HJ, Chen H, Wang D, Cui L   +10 more
doaj  

Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring

Frontiers in Physiology, 2015
Prenatal dexamethasone (DEX) exposure and high-fat (HF) intake are linked to hypertension. We examined whether maternal melatonin therapy prevents programmed hypertension synergistically induced by prenatal DEX plus postnatal HF in adult offspring.
You-Lin eTain, Jiunn-Ming eSheen, Hong-Ren eYu, Chih-Cheng eChen, Mao-Meng eTiao, Chien-Ning eHsu, Yu-Ju eLin, Kuang-Che eKuo, Li-Tung eHuang   +8 more
doaj   +1 more source

FROM DERMATOMYOSITIS TO OSTEOPOROSIS [PDF]

Romanian Journal of Medical Practice, 2019
Our aim is to describe a case of a menopausal woman who started with dermatomyositis and then became a patient at endocrinology because of complicated glucocorticoid osteoporosis.
Florica Sandru, Ana Valea, Simona Elena Albu, Mihai Cristian Dumitrascu, Mara Carsote   +4 more
doaj   +1 more source