Results 181 to 190 of about 2,551,103 (363)
Active domains in wild-type and mutant glucocorticoid receptors. [PDF]
Hans-Georg Dellweg+3 more
openalex +1 more source
Gout and NLRP3 Inflammasome Biology
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley +1 more source
Objective Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood disease classically attributed to innate immune cell dysregulation. This study aimed to elucidate the role of innate lymphoid cells (ILCs), including natural killer (NK) cells and helper‐ILCs (hILCs), in sJIA during clinically inactive disease (CID) through phenotypic and ...
Linda Quatrini+19 more
wiley +1 more source
Detection of glucocorticoid receptors on Friend erythroleukemia cells.
David W. Golde+3 more
openalex +1 more source
Margarita Arango-Lievano+5 more
semanticscholar +1 more source
Objective The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) treatment in patients with glucocorticoid (GC)‐dependent polymyalgia rheumatica (PMR). TCZ reduced GC dose and disease activity at week 24. This study aimed to assess relapse rates after stopping TCZ treatment in patients achieving remission at week 24.
Baptiste Chevet+24 more
wiley +1 more source
Targeting the glucocorticoid receptor in breast and prostate cancers
Jacob Kach, S. Conzen, R. Szmulewitz
semanticscholar +1 more source
Objective Autoimmune diseases, such as systemic lupus erythematosus (SLE), are associated with pulmonary arterial hypertension (PAH), a condition that can lead to heart failure. However, whether T cells also contribute to the occurrence of PAH in SLE has not been clarified.
Shuliang Jing+9 more
wiley +1 more source
Reactivation of thymocyte glucocorticoid receptors in a cell-free system.
Julianne J. Sando+2 more
openalex +1 more source