Results 201 to 210 of about 127,973 (266)

Short‐term clinical responses in horses and ponies treated with canagliflozin: A clinical field study

Equine Veterinary Journal, EarlyView.
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom, Sanna Truelsen Lindåse, Monika Wartel, Johan Bröjer   +3 more
wiley   +1 more source

An Ocular Surface‐Targeting Nucleic Acid Hydrogel for Efficient Dry Eye Disease Treatment

Exploration, EarlyView.
A self‐assembled nucleic acid hydrogel modified with mucin‐1 (MUC1) aptamer is developed, which can actively target the mucin layer on the ocular surface and significantly extend its retention time after distillation. Inside the hydrogel, therapeutic siRNA is embedded and can effectively silence the inflammation gene expression, subsequently restoring ...
Yuhe Liu, Zimeng Zhai, Yangyang Huang, Fujun Wang, Zifei Wang, Lijuan Zhu, Ka Jiang, Xujiao Zhou, Xingtao Zhou, Ying Jie, Xiuming Jin, Chuan Zhang, Jiaxu Hong   +12 more
wiley   +1 more source

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone-Glucocorticoid Receptor-LAMA5 Axis. [PDF]

Adv Sci (Weinh)
Zhang C, Song Y, Jin X, Xu Q, Ye H, Wu Z, Lin H, Hu J, Huang C, Zhou J, Lian J.   +10 more
europepmc   +1 more source

Impact of glucocorticoid receptor polymorphism rs6198 on sepsis survival in a prospective multicenter cohort. [PDF]

Sci Rep
Sombetzki C, Palmowski L, Ziehe D, Nowak H, Rahmel T, Ehrentraut SF, Thon P, Orlowski J, Bergmann L, Adamzik M, Koos B, Rump K, SepsisDataNet.NRW research group.   +12 more
europepmc   +1 more source

TENT5C functions as a corepressor in the ligand-bound glucocorticoid receptor and estrogen receptor α complexes. [PDF]

FEBS J
Li Y, Perera L, He RS, Baptissart M, Petrovich RM, Morgan M.   +5 more
europepmc   +1 more source

The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis. [PDF]

J Clin Invest
Durumutla HB, Haller A, Noble G, Prabakaran AD, McFarland K, Latimer H, Rajput A, Akinborewa O, Namjou-Khales B, Hui DY, Quattrocelli M.   +10 more
europepmc   +1 more source

Podocyte Glucocorticoid Receptor Expression and Treatment Outcome in Idiopathic Nephrotic Syndrome. [PDF]

Kidney Int Rep
van den Berge BT, Jansen J, Wetzels JFM, Smeets B, Maas RJ.   +4 more
europepmc   +1 more source

The role of relaxins in blood cell modulation: interactions with relaxin family peptide receptor 1 (RXFP1) and glucocorticoid receptor (GR). [PDF]

Clin Sci (Lond)
Broszkiewicz W, Domińska K.
europepmc   +1 more source