Results 191 to 200 of about 2,425,230 (388)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer

open access: yesCell Reports, 2018
Summary: Steroid hormone receptors are simultaneously active in many tissues and are capable of altering each other’s function. Estrogen receptor α (ER) and glucocorticoid receptor (GR) are expressed in the uterus, and their ligands have opposing effects
Jeffery M. Vahrenkamp   +10 more
doaj  

Transformation of the glucocorticoid receptor in rat liver cytosol by lysosomal enzymes.

open access: hybrid, 1979
Jan Carlstedt‐Duke   +4 more
openalex   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

open access: yesBMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan   +12 more
wiley   +1 more source

Glucocorticoid receptor stimulation and the regulation of neonatal cerebellar neural progenitor cell apoptosis

open access: yesNeurobiology of Disease, 2011
Glucocorticoids are used to treat respiratory dysfunction associated with premature birth but have been shown to cause neurodevelopmental deficits when used therapeutically.
Kevin K. Noguchi   +4 more
doaj  

Reactivation of thymocyte glucocorticoid receptors in a cell-free system.

open access: hybrid, 1977
Julianne J. Sando   +2 more
openalex   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Influence of patient‐specific factors when comparing multifidus fat infiltration between chronic low back pain patients and asymptomatic controls

open access: yesJOR SPINE, Volume 5, Issue 4, December 2022., 2022
Many studies have attempted to link multifidus fat infiltration with muscle quality and chronic low back pain, but there is no consensus on these relationships. This study suggests that when the presence of fat is not characteristic of an individual's age, sex, and BMI, it may be a back pain risk factor.
Alexander M. Ballatori   +10 more
wiley   +1 more source

Active domains in wild-type and mutant glucocorticoid receptors. [PDF]

open access: bronze, 1982
Hans-Georg Dellweg   +3 more
openalex   +1 more source

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