Results 291 to 300 of about 2,551,103 (363)

Clinical impact of real‐time androgen receptor alteration monitoring on metastatic castration‐resistant prostate cancer treatment in real‐world settings

International Journal of Cancer, EarlyView.
What's New? Androgen receptor (AR) alterations contribute to treatment resistance against androgen receptor signaling inhibitors in metastatic castration‐resistant prostate cancer. This real‐world study demonstrates that AR monitoring via liquid biopsy predicts treatment response and progression in metastatic castration‐resistant prostate cancer.
Regina Stitz, Franz Stoiber, Renè Silye, Elisabeth Rebhan, Michael Dunzinger, Franz Pühringer, Ellen Heitzer, Cornelia Hauser‐Kronberger   +7 more
wiley   +1 more source

Asoprisnil as a Novel Ligand Interacting with Stress-Associated Glucocorticoid Receptor. [PDF]

Biomedicines
Ejiohuo O, Bajia D, Pawlak J, Szczepankiewicz A.   +3 more
europepmc   +1 more source

The glucocorticoid receptor potentiates aldosterone-induced transcription by the mineralocorticoid receptor. [PDF]

Proc Natl Acad Sci U S A
Johnson TA, Fettweis G, Wagh K, Ceacero-Heras D, Krishnamurthy M, Sánchez de Medina F, Martínez-Augustin O, Upadhyaya A, Hager GL, Alvarez de la Rosa D.   +9 more
europepmc   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado, Erika N. Scott, Shahrad R. Rassekh, Catrina M. Loucks, Wan‐Chun Chang, Edward J. Raack, Jessica N. Trueman, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety Consortium   +9 more
wiley   +1 more source

Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for inflammation and cardiac hypertrophy. [PDF]

Front Endocrinol (Lausanne)
González FB, Pacini A, Castro A, Lioi S, Villar SR, D'Attilio L, Leiva RD, Favaloro L, Bottasso OA, Vigliano CA, Pérez AR.   +10 more
europepmc   +1 more source

Application of a protein-blotting procedure to the study of human glucocorticoid receptor interactions with DNA.

, 1987
C. M. Silva, D. B. Tully, L. A. Petch, C. M. Jewell, John A. Cidlowski   +4 more
openalex   +2 more sources

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

Glucocorticoid receptor occupancy of key bovine alphaherpesvirus 1 (BoHV-1) promoters correlates with chromatin remodeling during reactivation from latency. [PDF]

J Virol
Ostler JB, Jones C.
europepmc   +1 more source

Protein kinase activity can be separated from the purified activated rat liver glucocorticoid receptor.

, 1987
Olga Perišić, Marija Radojčić, D Kanazir   +2 more
openalex   +1 more source

Telomere‐Related Gene Networks in the Ovary Shift Across Environmental Factors

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ovary is key to linking environmental factors with the timing and quality of offspring development. Focused on free‐living female tree swallows (Tachycineta bicolor), we measured temporal variation in ovarian expression of genes involved in the regulation of telomere length.
Sarah E. Wolf, Elizabeth M. George, Jess Dong, Kimberly A. Rosvall   +3 more
wiley   +1 more source