Results 111 to 120 of about 291,048 (366)
Advanced Science, EarlyView.This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni +12 more
wiley +1 more source
Regulation of stem cell factor expression in inflammation and asthma
Memorias do Instituto Oswaldo Cruz, 2005 Stem cell factor (SCF) is a major mast cell growth factor, which could be involved in the local increase of mast cell number in the asthmatic airways.
Carla A Da Silva, Nelly Frossard
doaj +1 more source
Psychophysiological response to social stressors : relevance of sex and age [PDF]
, 2018 Understanding the factors involved in the psychophysiological response of people in acute stressful situations is crucial to the prevention and treatment of stress-related health problems. We aim to integrate the results of studies investigating the role
Hidalgo, Vanesa +3 more
core +3 more sources
Adrenocortical Hyperfunction Associated with Hirsutism, Obesity, Hypertension and Normal Glucocorticoid Secretion [PDF]
, 1955 Oliver Garrod, A. E. Kellie
openalex +1 more source
Advanced Science, EarlyView.Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin +6 more
wiley +1 more source
Scientific Reports, 2017 Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP.
Hyun-Woo Yang +4 more
doaj +1 more source
Lifetime glucocorticoid profiles in baleen of right whale calves: Potential relationships to chronic stress of repeated wounding by Kelp Gulls [PDF]
, 2018 Baleen tissue accumulates stress hormones (glucocorticoids, GC) as it grows, along with other adrenal, gonadal and thyroid hormones. The hormones are deposited in a linear fashion such that a single plate of baleen allows retrospective assessment and ...
Ajó, Alejandro A. Fernández +7 more
core +1 more source
Advanced Science, EarlyView.Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang +6 more
wiley +1 more source
Effect of glucocorticoids on the oxidative desaturation of fatty acids by rat liver microsomes.
Journal of Lipid Research, 1979 The effect of glucocorticoids on the oxidative desaturation of fatty acids by liver microsomal preparations of rats has been studied. Hydrocortisone produced a significant decrease in the conversion of [1-14C]linoleic acid to gamma-linolenic acid and [1 ...
I N de Gómez Dumm +2 more
doaj +1 more source
Critical roles of endogenous glucocorticoids for disease tolerance in malaria
, 2019 During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien +4 more
core +1 more source