Results 101 to 110 of about 241,090 (306)
Use of systemic glucocorticoids and the risk of colorectal cancer
, 2013 Systemic glucocorticoids are potent immunosuppressants, potentially facilitating carcinogenesis.
Ostenfeld, E B +9 more
core +1 more source
Glucocorticoids in the control of neuroinflammation [PDF]
, 2007 Glucocorticoids are a class of steroid hormones that are endowed with profound anti-inflammatory and immunosuppressive activities. Endogenous glucocorticoids are key players in the modulation of the immune system and establish an endocrine basis of many ...
Reichardt, Holger M. +4 more
core +1 more source
Hybrid Biofabrication of a Hierarchically Organized Periosteum‐Inspired In Vitro Platform
Advanced Healthcare Materials, EarlyView.A hybrid biofabrication strategy integrates melt electrowriting with extrusion‐based 3D bioprinting to create a hierarchically organized periosteum‐inspired in vitro platform. Spatially defined osteogenic, fibrous, and endothelial cell‐containing compartments support long‐term culture, osteogenic maturation, and CD31+ endothelial cell organization ...
Yakui Liu +7 more
wiley +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
Advanced Science, EarlyView.A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
Glucocorticoids use in RMD patients
Glucocorticoids use in RMD ...
Fatima Alnaimat
core +1 more source
Chinese Journal of Lung Cancer, 2019 Immunocheckpoint inhibitors (ICIs) activated the patients’ tumor immunity to kill the tumor cell, and brought new hope to patients with tumor. However, a series of immunocheckpoint inhibitors related adverse effects (irAEs) may also occur based on immune
Hanping WANG +6 more
doaj +1 more source
Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction
Advanced Science, EarlyView.In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng +12 more
wiley +1 more source
Glucocorticoids and the skin [PDF]
, 1995 Glucocorticoids are the most effective anti -inflammatory agents currently available, but a variety of adverse effects limit their clinical usefulness.
Teelucksingh, Surujpal
core
Glucocorticoids in T Cell Development and Function
, 2000 Glucocorticoids are small lipophilic compounds that mediate their many biological effects by binding an intracellular receptor (GR) that, in turn, translocates to the nucleus and directly or indirectly regulates gene transcription.
Jonathan D. Ashwell +2 more
core +1 more source