Results 111 to 120 of about 173,033 (308)

Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index

open access: yesCanadian Respiratory Journal, 1999
In children with persistent asthma, inhaled glucocorticoids decrease symptoms and exacerbations, decrease the need for rescue bronchodilator medications, improve airway patency and reduce airway hyperresponsiveness.
F Estelle R Simons
doaj   +1 more source

Regulation of stem cell factor expression in inflammation and asthma

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Stem cell factor (SCF) is a major mast cell growth factor, which could be involved in the local increase of mast cell number in the asthmatic airways.
Carla A Da Silva, Nelly Frossard
doaj   +1 more source

Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to investigate lifestyle‐related factors in patients with psoriatic arthritis (PsA) and their association with disease activity measurements. Methods This multicenter cohort included 938 patients who were newly diagnosed with PsA between 2013 and 2023.
Batoul Hojeij   +11 more
wiley   +1 more source

Glucocorticoids in T Cell Development and Function [PDF]

open access: yes, 2000
Glucocorticoids are small lipophilic compounds that mediate their many biological effects by binding an intracellular receptor (GR) that, in turn, translocates to the nucleus and directly or indirectly regulates gene transcription.
Jonathan D. Ashwell   +2 more
core   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

Tachyphylaxis to topical glucocorticoids; what is the evidence? [PDF]

open access: yes, 2013
Background: Common belief holds that as topical glucocorticoids are used over time the less effective they become, a phenomenon called tolerance or tachyphylaxis.Objective: To determine what evidence supports the concept of tachyphylaxis to ...
Feldman, Steven R.   +2 more
core   +1 more source

Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways

open access: yesScientific Reports, 2017
Chronic rhinosinusitis with nasal polyps (CRSwNP) is closely associated with tissue remodeling. Epithelial-to-mesenchymal transition (EMT), a process of tissue remodeling, can be a therapeutic target of CRSwNP.
Hyun-Woo Yang   +4 more
doaj   +1 more source

Glucocorticoids and the skin [PDF]

open access: yes, 1995
Glucocorticoids are the most effective anti -inflammatory agents currently available, but a variety of adverse effects limit their clinical usefulness.
Teelucksingh, Surujpal
core  

Exogenous glucocorticoids and adverse cerebral effects in children [PDF]

open access: yes, 2011
Glucocorticoids are commonly used in treatment of paediatric diseases, but evidence of associated adverse cerebral effects is accumulating. The various pharmacokinetic profiles of the exogenous glucocorticoids and the changes in pharmacodynamics during ...
Paulson, Olaf B   +7 more
core   +1 more source

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