Results 271 to 280 of about 287,603 (362)

Clinical impact of real‐time androgen receptor alteration monitoring on metastatic castration‐resistant prostate cancer treatment in real‐world settings

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Androgen receptor (AR) alterations contribute to treatment resistance against androgen receptor signaling inhibitors in metastatic castration‐resistant prostate cancer. This real‐world study demonstrates that AR monitoring via liquid biopsy predicts treatment response and progression in metastatic castration‐resistant prostate cancer.
Regina Stitz   +7 more
wiley   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Probiotics restore enteric HDL3 secretion and improve prognosis in patients with end‐stage renal disease

open access: yesiMeta, EarlyView.
Randomized double‐blind trials have shown that probiotic mixtures significantly increase high‐density lipoprotein (HDL) levels and reduce the risk of cardiovascular disease mortality in end‐stage renal disease (ESRD) patients. Meta‐analysis with prospective cohort studies further confirms that elevated HDL is a protective factor for ESRD outcomes.
Xiaoxue Liu   +30 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

Machine Learning Reveals the Value of Unconventional T Lymphocytes in Sepsis and Prognosis of Elderly Patients With Severe Lower Respiratory Tract Infections

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 14, July 2025.
Initially, 166 subjects aged 65 years or older with severe LRTIs met the diagnostic criteria, but 30 cases were excluded due to incomplete clinical data, and 17 cases were excluded due to the presence of malignancies, connective tissue diseases, or long‐term use of immunosuppressive agents. Ultimately, 119 patients were included in the study. The study
Tianqi Qi   +8 more
wiley   +1 more source

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