Results 271 to 280 of about 173,033 (308)
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Journal of Asthma, 1994
Glucocorticoids act on calcium metabolism at many levels to produce osteoporosis, the major pathogenic effect probably being an inhibition of bone formation. In men, this is likely to be contributed to by a dose-related reduction in circulating testosterone concentrations.
I R, Reid, A G, Veale, J T, France
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Glucocorticoids act on calcium metabolism at many levels to produce osteoporosis, the major pathogenic effect probably being an inhibition of bone formation. In men, this is likely to be contributed to by a dose-related reduction in circulating testosterone concentrations.
I R, Reid, A G, Veale, J T, France
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Glucocorticoids and Lipocortin
1989One of the responses of an animal to injury, infection or other stresses is the release from the adrenal cortex of glucocorticosteroids(GCs). In humans this is predominantly hydrocortisone (cortisol), but other animals may release different but related steroids. For a long while it was believed that steroids were in some way involved in the mounting of
S. H. Peers, R. J. Flower
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Annales d'Endocrinologie, 2018
Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the most frequent cause of osteoporosis in young people. Bone loss and fracture risk increase rapidly after the initiation of corticosteroid therapy and are proportional to dose and treatment duration.
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Corticosteroid-induced osteoporosis is the most common form of secondary osteoporosis and the most frequent cause of osteoporosis in young people. Bone loss and fracture risk increase rapidly after the initiation of corticosteroid therapy and are proportional to dose and treatment duration.
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1989
More than 30 years ago the first report concerning the therapeutic use of glucocorticoids appeared. Even if the pediatrician is aware of the large number of clinical and experimental studies that have accumulated during the past three decades he is still faced with the uncertainties of corticosteroid therapy in children’s diseases especially with ...
D, Reinhardt, M, Griese
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More than 30 years ago the first report concerning the therapeutic use of glucocorticoids appeared. Even if the pediatrician is aware of the large number of clinical and experimental studies that have accumulated during the past three decades he is still faced with the uncertainties of corticosteroid therapy in children’s diseases especially with ...
D, Reinhardt, M, Griese
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1979
Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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Steroids in general and glucocorticoids in particular affect lysosomes in various ways. The explanation of these effects remains in dispute, however. Theories include the view that steroids interact directly with lysosomal membranes, that steroids provoke induced changes in lysosomes, and that classical steroid receptors originate in lysosomes ...
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2015
The lung is a major clinical target of glucocorticoid-based therapeutics, and GR signaling has broad effects on respiratory physiology and inflammation. During lung development, expression of GR in the mesenchyme is required for normal terminal alveolar epithelial differentiation.
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The lung is a major clinical target of glucocorticoid-based therapeutics, and GR signaling has broad effects on respiratory physiology and inflammation. During lung development, expression of GR in the mesenchyme is required for normal terminal alveolar epithelial differentiation.
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Aging Clinical and Experimental Research, 1995
Information on the role of glucocorticoids in the aging of vertebrate species is reviewed. There is strong evidence that elevated plasma glucocorticoid levels have a causal role in the rapid deterioration following reproduction in semelparous vertebrate species.
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Information on the role of glucocorticoids in the aging of vertebrate species is reviewed. There is strong evidence that elevated plasma glucocorticoid levels have a causal role in the rapid deterioration following reproduction in semelparous vertebrate species.
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2002
Corticosteroids are highly effective anti-inflammatory therapy in asthma, and the molecular mechanisms involved in suppression of allergic inflammation are now better understood (Barnes 1998, 2001). Corticosteroids are effective clinically because they block many of the inflammatory pathways that are abnormally activated in asthma and they have a very ...
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Corticosteroids are highly effective anti-inflammatory therapy in asthma, and the molecular mechanisms involved in suppression of allergic inflammation are now better understood (Barnes 1998, 2001). Corticosteroids are effective clinically because they block many of the inflammatory pathways that are abnormally activated in asthma and they have a very ...
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