Results 31 to 40 of about 415,196 (303)
Glucocorticoids and “Stress” Are Not Synonymous
Integrative Organismal Biology, 2019 Synopsis Reference to glucocorticoids as “stress hormones” has been growing in prevalence in the literature, including in comparative and environmental endocrinology.
S. MacDougall-Shackleton +3 more
semanticscholar +1 more source
気管支喘息患者の血清コーチゾール値について. 副腎皮質ホルモン投与および年齢との関連 [PDF]
, 1995 Serum cortisol levels were examined in 94 patients with bronchial asthma in relation to dose of glucocorticoids and age. 1. The level of serum cortisol was significantly lower in group A patients, treated with glucocorticoids (prednisolone of 5mg/day or ...
Harada, Hideo +9 more
core +1 more source
, 2016 The most effective anti-inflammatory drugs used to treat patients with airways disease are topical glucocorticosteroids (GCs). These act on virtually all cells within the airway to suppress airway inflammation or prevent the recruitment of inflammatory cells into the airway.
Adcock, IM, Mumby, S
openaire +4 more sources
Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]
, 2016 Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto +1 more
core +1 more source
The influence of glucocorticoids on neuronal survival and synaptic function
Biomolecular Concepts, 2012 Glucocorticoids, recognized as stress-related steroid hormones secreted from adrenal glands, have multiple roles in brain function. The concentration of glucocorticoids is regulated by the hypothalamic-pituitary-adrenal axis, and chronically elevated ...
Numakawa Tadahiro +4 more
doaj +1 more source
Use of glucocorticoids in the management of immunotherapy‐related adverse effects
Thoracic Cancer, 2020 Immune checkpoint inhibitors (ICIs) activate host antitumor immunity to kill tumor cells. However, ICI therapy may be accompanied by a series of immunotherapy‐related adverse effects (irAEs) caused by activated autoreactive T cells.
Hanping Wang +6 more
doaj +1 more source
Improvement of Treg immune response after treatment with tocilizumab in giant cell arteritis
Clinical & Translational Immunology, 2021 Objectives To study the percentage, suppressive function and plasticity of Treg in giant cell arteritis (GCA), and the effects of glucocorticoids and tocilizumab.
Maxime Samson +27 more
doaj +1 more source
Obstetric Medicine, 2019 The physiological changes that occur during pregnancy include altered regulation of the hypothalamo-pituitary-adrenal axis. The fetoplacental unit plays a major role in this, together with alteration of circulating cortisol-binding globulin levels, with a net effect to increase both total and free cortisol levels.
Riccardo Pofi +2 more
openaire +5 more sources
気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]
, 2002 Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo +8 more
core +1 more source
Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus
Cell Reports, 2019 Summary: Glucocorticoids are lipid-soluble hormones that signal via the glucocorticoid receptor (GR), a ligand-dependent transcription factor. Circulating glucocorticoids derive from the adrenals, but it is now apparent that paracrine glucocorticoid ...
Matthew D. Taves +4 more
doaj +1 more source