Results 101 to 110 of about 3,865 (217)

Mass spectrometry imaging of glucosinolates in arabidopsis flowers and siliques [PDF]

, 2012
Glucosinolates are multi-functional plant secondary metabolites which play a vital role in plant defence and are, as dietary compounds, important to human health and livestock well-being.
Cramer, Rainer, Koroleva, O. A., Sarsby, J., Stain, Chris, Towers, M. W.   +4 more
core   +1 more source

High-level and reusable preparation of sulforaphane by yeast cells expressing myrosinase

Food Chemistry: X, 2023
Myrosinase is a key tool for the fast and efficient preparation of sulforaphane which is one of the prominent natural ingredients found in brassicaceous vegetables.
Lili Wang, Hamed I. Hamouda, Yueyang Dong, Hong Jiang, Yongyi Quan, Yimiao Chen, Yan Liu, Jiaqi Wang, Mohamed A. Balah, Xiangzhao Mao   +9 more
doaj   +1 more source

Production of plant-derived anticancer precursor glucoraphanin in chromosomally engineered Escherichia coli

Microbiological Research, 2020
Glucoraphanin is a methionine-derived glucosinolate that imparts numerous health-benefits with broad bioactivity. Low amounts in plant tissues and high cost of extraction have limited the production of glucoraphanin. Metabolic engineering in heterologous microorganisms is an attractive approach to achieve efficient production of valuable natural ...
Han, Yang, Jiayang, Qin, Xiuwen, Wang, Hamed M, Ei-Shora, Bo, Yu   +4 more
openaire   +2 more sources

Identification and Biological Characterization of a Novel NRF2 Activator Molecule Released From the Membranes of Heat‐Treated Bifidobacterium breve NCC 2950

Molecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
We have shed light on the mode of action behind the postbiotic form of Bifidobacterium breve NCC 2950. Heat treatment of this strain at 90°C leads to the production of 4‐oxo‐2‐pentenoic acid (OPA), which activates NRF2 host response, improving oxidative stress resistance and decreasing inflammation. ABSTRACT Postbiotics are defined as a “preparation of
Francis Foata, Stéphane Duboux, Sébastien Herzig, Federico Sizzano, Jonathan Thevenet, Philippe Guy, Serge Rezzi, Sylviane Métairon, Bertrand Bourqui, Ivan Montoliu, Annick Mercenier, Nabil Bosco   +11 more
wiley   +1 more source

Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective

Frontiers in Pharmacology, 2018
Depression is one of the most common mood disorders with a high rate of relapse. Accumulating evidence suggests that the transcription factor Kelch-like erythroid cell-derived protein with CNC homology (ECH)-associated protein 1 (Keap1)-Nuclear factor ...
Kenji Hashimoto
doaj   +1 more source

Glucosinolate hydrolysis and bioavailability of resulting isothiocyanates: Focus on glucoraphanin

Journal of Functional Foods, 2014
There is a growing interest in the health benefits of broccoli. Sulforaphane, the major bioactive component in broccoli, is an unstable isothiocyanate stored in the plant as glucoraphanin. Myrosinase enzymes release sulforaphane when the plant is crushed. Extraction during supplement formulation or heat processing can destroy myrosinase.
Angelino D., Jeffery E.
openaire   +3 more sources

Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The VEgetableS for vaScular hEaLth (VESSEL) study

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4300-4310, August 2025.
Abstract Aims Higher cruciferous vegetable (e.g., broccoli) intake is associated with lower risk of type 2 diabetes and cardiovascular disease, but limited causal evidence exists. We investigated if cruciferous vegetable intake improved glycaemic control compared to root/squash vegetables in non‐diabetic adults with elevated blood pressure.
Emma L. Connolly, Alex H. Liu, Richard J. Woodman, Armaghan Shafaei, Lisa G. Wood, Richard Mithen, Anthony P. James, Carl J. Schultz, Seng Khee Gan, Catherine P. Bondonno, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst   +12 more
wiley   +1 more source

Broccoli Sprouts as Functional Food: Phytochemical Profile and Antioxidant Activity Linked to Human Health

Applied Sciences
Background: Recent research has focused on diet as a potential source of antioxidants in the context of both human health and disease prevention. Among the many plant-derived antioxidants, sulforaphane (SFN) has emerged as a potent phytochemical in the ...
Andreea-Maria Mitran, Ionut Iulian Lungu, Ioana Cezara Caba, Cornelia Mircea, Silvia Robu, Alina Stefanache, Paula Rusu, Ioana Mita-Baciu, Monica Hancianu, Oana Cioanca   +9 more
doaj   +1 more source

The study of Zn2+ and Cu2+ effects on myrosinase activity and sulforaphane production in Lepidium draba [PDF]

مجله بیوتکنولوژی کشاورزی, 2016
Myrosinase is a β-thioglucoside glucohydrolase enzyme which catalyzses the separation of glucose from glucosinolates and produces an unstable intermediate, aglycone.
Mehdi Mohammadi, Ali Riyahi, Shahram Pour Seyyedi, Maryam Amini Zadeh   +3 more
doaj   +1 more source

Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky, Mohammed E. Abo‐El Fetoh, Safaa A. Faheem, Abdullah F. Radwan, Mariam H. Fawzy, Aya M. Mustafa, Mohamed A. Said, Daniela Calina, Javad Sharifi‐Rad, William C. Cho   +9 more
wiley   +1 more source