Results 81 to 90 of about 3,475 (207)

Application of Tryptophan and Methionine in Broccoli Seedlings Enhances Formation of Anticancer Compounds Sulforaphane and Indole-3-Carbinol and Promotes Growth

Foods
Broccoli is a popular cruciferous vegetable that is well known for its abundant health-promoting biochemicals. The most important of these beneficial biochemicals are glucosinolates, including glucoraphanin and glucobrassicin.
Rui Li, Zihuan Zhou, Xiaofei Zhao, Jing Li   +3 more
doaj   +1 more source

A Physiological-Based Model for Simulating the Bioavailability and Kinetics of Sulforaphane from Broccoli Products

Foods, 2021
There are no known physiological-based digestion models that depict glucoraphanin (GR) to sulforaphane (SR) conversion and subsequent absorption. The aim of this research was to make a physiological-based digestion model that includes SR formation, both ...
Quchat Shekarri, Matthijs Dekker
doaj   +1 more source

Unravelling Glucoraphanin and Glucoerucin Metabolism across Broccoli Sprout Development: Insights from Metabolite and Transcriptome Analysis

Plants
Variations in the concentration of glucoraphanin (GRA) and glucoerucin (GER), as well as the corresponding breakdown products, isothiocyanates (ITCs) and nitriles, were investigated during the growth of broccoli sprouts. The concentrations of GRA and GER
Jiansheng Wang, Yusen Shen, X. Sheng, Huifang Yu, Mengfei Song, Qiaomei Wang, H. Gu   +6 more
semanticscholar   +1 more source

CRISPR-Cas9-Mediated Gene Editing of MYB28 Genes Impair Glucoraphanin Accumulation of Brassica oleracea in the Field

The CRISPR Journal, 2021
Discoveries in model plants grown under optimal conditions can provide important directions for crop improvement. However, it is important to verify whether results can be translated to crop plants grown in the field.
Mikhaela Neequaye, Sophia Stavnstrup, W. Harwood, T. Lawrenson, Penny A C Hundleby, J. Irwin, Perla Troncoso-Rey, S. Saha, M. Traka, R. Mithen, L. Østergaard   +10 more
semanticscholar   +1 more source

Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers

Food Frontiers, Volume 7, Issue 3, May 2026.
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz, Alejandra Romero‐Montero, Hector Hernández‐Parra, Sheila I. Peña‐Corona, Héctor Adrián García‐Gasca, Katya Carbone, Fabio Gervasi, Shivaprasad Shetty Mangalpady, Rajesh Kaverikana, Mariia Shanaida, Volodymyr Shanaida, Daniela Calina, Javad Sharifi‐Rad, Gerardo Leyva‐Gómez   +13 more
wiley   +1 more source

Role of Extracellular Vesicles (EVs) in Mediating Antioxidant Response to a Glucoraphanin Rich Meal

Proceedings of the Nutrition Society
Aging is associated with increasing oxidative stress and declining antioxidant defences, making the body susceptible to various chronic conditions. Cruciferous vegetables contain glucoraphanin, which is metabolised into sulforaphane (SFN) in the gut(1 ...
N. Mitra, F. Ramzan, H.H. Phua, C. Blenkiron, A. Artuyants, C. Pook, F. Lithander, M. Foster, R. Mithen   +8 more
semanticscholar   +1 more source

Assessment of additional information related to genetically modified oilseed rape MS11 (application EFSA‐GMO‐BE‐2016‐138)

EFSA Journal, Volume 24, Issue 4, April 2026.
Abstract In a previous scientific opinion on application EFSA‐GMO‐BE‐2016‐138, the EFSA Panel on Genetically Modified Organisms (GMO Panel) could not conclude on the comparative analysis and on the food and feed safety assessment of genetically modified (GM) oilseed rape MS11 because of the lack of an appropriate compositional data set.
EFSA Panel on Genetically Modified Organisms (GMO), Josep Casacuberta, Francisco Barro, Albert Braeuning, Ruud de Maagd, Michelle M. Epstein, Thomas Frenzel, Jean‐Luc Gallois, Frits Koning, Antoine Messéan, F. Javier Moreno, Fabien Nogué, Giovanni Savoini, Alan H. Schulman, Christoph Tebbe, Eve Veromann, Michele Ardizzone, Giacomo De Sanctis, Antonio Fernandez Dumont, Arianna Ferrari, Andrea Gennaro, Tilemachos Goumperis, Franco Maria Neri   +22 more
wiley   +1 more source

Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials

Frontiers in Oncology, 2023
ObjectivesThis paper presents a systematic review aimed at assessing the therapeutic potential of sulforaphane (SFN) in the treatment of diverse cancer types.MethodsFollowing Cochrane guidelines for systematic reviews, we conducted an exhaustive search ...
Dana ElKhalifa, Nour Al-Ziftawi, Ahmed Awaisu, Feras Alali, Ashraf Khalil   +4 more
doaj   +1 more source

Bioaccessible Sulforaphane Drives Macrophage Migration and Differentiation by Reprogramming the Interleukin Profile in Intestinal Inflammation

BioFactors, Volume 52, Issue 2, March/April 2026.
Bioaccessible Sulforaphane Drives Macrophage Migration and Differentiation by Reprogramming the Interleukin Profile in Intestinal Inflammation. ABSTRACT Inflammatory bowel disease (IBD) arises from dysregulated interactions between the immune system and the intestinal microenvironment.
Sonia Medina, Concepción Medrano‐Padial, Cristina García‐Viguera, Raúl Domínguez‐Perles   +3 more
wiley   +1 more source

Broccoli Sprouts as Functional Food: Phytochemical Profile and Antioxidant Activity Linked to Human Health

Applied Sciences
Background: Recent research has focused on diet as a potential source of antioxidants in the context of both human health and disease prevention. Among the many plant-derived antioxidants, sulforaphane (SFN) has emerged as a potent phytochemical in the ...
Andreea-Maria Mitran, Ionut Iulian Lungu, Ioana Cezara Caba, Cornelia Mircea, Silvia Robu, Alina Stefanache, Paula Rusu, Ioana Mita-Baciu, Monica Hancianu, Oana Cioanca   +9 more
doaj   +1 more source