Results 71 to 80 of about 2,817 (157)

Glucosinolate and Isothiocyanate Profiles in Different Varieties of Raphanus sativus Seed via Multivariate Data Analysis

AgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 2, Page 141-151, June 2026.
Through HPLC–MS/MS analysis and multivariate statistics, raphani semen (RS) varieties with high functional components were screened. The white raphani semen “Xuebawang” was identified as ideal for further study due to its high bioactive content: glucoraphenin (9010.27 mg/100 g), glucoraphanin (1027.76 mg/100 g), sulforaphane (66.14 mg/100 g), and ...
Yonghua Li, Dongmei Lin, Peng Wu, Rui Gao, Jingxiu Bi, Yuying Jiang, Tong Zhao, Xuexia Yuan, Jianhan Xu, Pingxiang Liu, Yutao Wang   +10 more
wiley   +1 more source

Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial [PDF]

, 2019
Background Epidemiological evidence suggests that consumption of cruciferous vegetables is associated with reduced risk of prostate cancer progression, largely attributed to the biological activity of glucosinolate degradation products, such as ...
O'Neill, Carmel M, Savva, George M, Coode-Bate, Jack, Troncoso-Rey, Perla, Saha, Shikha, Needs, Paul W, Hughes, Jackie, Al Kadhi, Omar, Traka, Maria H, Defernez, Marianne, Cooper, Colin S, Mythen, Laura, Bernuzzi, Federico, Ball, Richard Y, Mithen, Richard F, Kibblewhite, Helen, Dainty, Jack R, Mills, Robert D, Melchini, Antonietta   +18 more
core   +1 more source

Impact of spring rape varieties on protein extraction from press cake, emulsifying properties and antinutrient content

Journal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4613-4622, June 2026.
Abstract BACKGROUND Rapeseed is the second most cultivated oilseed globally after soybean and a protein‐rich press cake is generated after liberation of the oil. However, its use in food applications is limited by high levels of anti‐nutrients such as glucosinolates and phytic acid. Although differences between botanical varieties are known, controlled
Cecilia Ahlström, Evangelia Papagianni, Eu Sheng Wang, Inger‐Cecilia Mayer Labba, Ann‐Sofie Sanberg, Emil Andersson, Johan Thuvander, Karolina Östbring   +7 more
wiley   +1 more source

Restoration of Immune Surveillance in Prostate Cancer Prevention by Sulforaphane in Hi‐Myc Mice

Molecular Carcinogenesis, Volume 65, Issue 6, Page 677-686, June 2026.
ABSTRACT Oral administration of broccoli constituent sulforaphane (SFN) prevents prostate cancer development in preclinical mouse models. However, the mechanism(s) underlying prostate cancer prevention by SFN are not fully understood. In this study, we used a human relevant mouse model (Hi‐Myc mice) to demonstrate restoration of immune surveillance by ...
Krishna B. Singh, Eun‐Ryeong Hahm, Joshi J. Alumkal, Shivendra V. Singh   +3 more
wiley   +1 more source

Long-Term Intake of Glucoraphanin-Enriched Kale Suppresses Skin Aging via Activating Nrf2 and the TβRII/Smad Pathway in SAMP1 Mice

, 2019
Sulforaphane, a potent antioxidant compound, is unstable at ambient temperature, whereas its precursor glucoraphanin is stable and metabolized to sulforaphane. Thus, we hypothesized that glucoraphanin-rich diet could effectively induce antioxidant enzyme
Saki Ichikawa, Soichiro Nakamura (1901200), Saki Ichikawa (1746319), Yuki Uchibori (7296035), Shigeru Katayama (1901203), Yuki Uchibori, Shigeru Katayama, Supatta Chawalitpong (4692445), Supatta Chawalitpong, Soichiro Nakamura   +9 more
core   +1 more source

Glucosinolate–Myrosinase Formulations for Adult Obesity: Towards Next Generation of Bioactive Therapies

Foods
The rising global prevalence of obesity and metabolic disorders calls for innovative dietary strategies that can modulate key enzymatic pathways involved in lipid and carbohydrate metabolism.
Concepción Medrano-Padial, Cassidy Bo Harris, Verónica Mellado-Romero, Raúl Domínguez-Perles, Diego A. Moreno   +4 more
doaj   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, Volume 40, Issue 6, Page 3250-3266, June 2026.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Plant-derived bioactives, the gut–brain axis, and neurodegenerative diseases: mechanistic roles of diet–microbiota interactions

Frontiers in Neuroscience
Diet is increasingly recognized as a potential upstream modulator of the gut-brain axis (GBA) through its effects on the microbiome, microbial metabolites, and host immune and endocrine responses.
Ashley Reynolds, Ethan Glenn, Brigitte Lavoie, Suzanne L. Ishaq, Yanyan Li   +4 more
doaj   +1 more source

How Glucosinolates Affect Generalist Lepidopteran Larvae: Growth, Development and Glucosinolate Metabolism

Frontiers in Plant Science, 2017
Multiple lepidopteran larvae feed successfully on plants containing glucosinolates despite the diverse array of toxic and deterrent breakdown products, such as isothiocyanates (ITCs), formed upon plant damage.
Verena Jeschke, Emily E. Kearney, Katharina Schramm, Grit Kunert, Anton Shekhov, Jonathan Gershenzon, Daniel G. Vassão   +6 more
doaj   +1 more source

1,2,6‐Thiadiazin‐4‐ones: Robust Photocatalysts for the Green Aerobic Oxidation of Sulfides to Sulfoxides

European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.
A new photocatalyst for the aerobic photochemical oxidation of sulfides to sulfoxides is described under really low catalyst loading (0.01 mol%) and methanol as the green solvent. The chemoselective oxidation of sulfides to sulfoxides is accomplished using a new family of photocatalysts, namely 1,2,6‐thiadiazin‐4‐ones. Utilizing a low catalyst loading (
Charikleia I. Karaousta, Stamatis K. Serviou, Chrysanthi K. Spyropoulou, Nikolaos Stavridis, Andreas S. Kalogirou, Panayiotis A. Koutentis, Christoforos G. Kokotos   +6 more
wiley   +1 more source