Results 71 to 80 of about 1,963 (164)

Bioaccessible Sulforaphane Drives Macrophage Migration and Differentiation by Reprogramming the Interleukin Profile in Intestinal Inflammation

BioFactors, Volume 52, Issue 2, March/April 2026.
Bioaccessible Sulforaphane Drives Macrophage Migration and Differentiation by Reprogramming the Interleukin Profile in Intestinal Inflammation. ABSTRACT Inflammatory bowel disease (IBD) arises from dysregulated interactions between the immune system and the intestinal microenvironment.
Sonia Medina, Concepción Medrano‐Padial, Cristina García‐Viguera, Raúl Domínguez‐Perles   +3 more
wiley   +1 more source

The effect of chewing on oral glucoraphanin hydrolysis in raw and steamed broccoli

Journal of Functional Foods, 2018
Chewing disrupts broccoli cells, and myrosinase can effectively hydrolyze the glucosinolate glucoraphanin into the biological active sulforaphane. The influence of chewing time and steaming time on glucoraphanin hydrolysis as well as sulforaphane and sulforaphane nitrile formation in broccoli was studied.To study the effect of chewing time on ...
Sarvan, Irmela, van der Klauw, Michelle, Oliviero, Teresa, Dekker, Matthijs, Verkerk, Ruud   +4 more
openaire   +2 more sources

The Antimicrobial Effects of Myrosinase Hydrolysis Products Derived from Glucosinolates Isolated from Lepidium draba

Plants
Lepidium draba (hoary cress) is a perennial plant belonging to the Brassicaceae family that produces two dominant glucosinolates (GLSs): glucoraphanin (GRN) and sinalbin (SBN).
Zoltán Polozsányi, Helena Galádová, Michal Kaliňák, Martin Jopčík, Barbora Kaliňáková, Albert Breier, Martin Šimkovič   +6 more
doaj   +1 more source

Variation in herbivore defense strategies among plant species differing in elevational distribution and the role of temperature in defense

New Phytologist, Volume 249, Issue 6, Page 3091-3103, March 2026.
Summary Temperature influences the distribution and performance of both plants and insect herbivores. Consequently, plant–herbivore interactions are likely to vary across thermal gradients, which could affect the evolution of plant defense. Furthermore, temperature fluctuations may elicit immediate changes in defense.
Thomas Dorey, Janisse Deluigi, Alessio Maccagni, Sergio Rasmann, Gaétan Glauser, Yvonne Willi   +5 more
wiley   +1 more source

Dietary intake of glucoraphanin during pregnancy and lactation prevents the behavioral abnormalities in the offspring after maternal immune activation

Neuropsychopharmacology Reports, 2020
Aim Epidemiological data suggest that maternal immune activation (MIA) plays a role in the etiology of neuropsychiatric disorders including autism spectrum disorder (ASD) and schizophrenia. However, there is no prophylactic nutrition that can prevent the
Yuko Fujita, Atsuhiro Fujita, Tamaki Ishima, Ayumi Hirai, Shigenori Suzuki, Hiroyuki Suganuma, Kenji Hashimoto   +6 more
doaj   +1 more source

Production of plant-derived anticancer precursor glucoraphanin in chromosomally engineered Escherichia coli

Microbiological Research, 2020
Glucoraphanin is a methionine-derived glucosinolate that imparts numerous health-benefits with broad bioactivity. Low amounts in plant tissues and high cost of extraction have limited the production of glucoraphanin. Metabolic engineering in heterologous microorganisms is an attractive approach to achieve efficient production of valuable natural ...
Han, Yang, Jiayang, Qin, Xiuwen, Wang, Hamed M, Ei-Shora, Bo, Yu   +4 more
openaire   +2 more sources

Sulforaphane is Superior to Glucoraphanin in Modulating Carcinogen-Metabolising Enzymes in Hep G2 Cells

Asian Pacific Journal of Cancer Prevention, 2013
Glucoraphanin is the main glucosinolate found in broccoli and other cruciferous vegetables (Brassicaceae). The objective of the study was to evaluate whether glucoraphanin and its breakdown product sulforaphane, are potent modulators of various phase I and phase II enzymes involved in carcinogen-metabolising enzyme systems in vitro.
Abdull Razis, Ahmad Faizal, Mohd Noor, Noramaliza   +1 more
openaire   +3 more sources

Profiling the Bioactive Compounds in Broccoli Heads with Varying Organ Sizes and Growing Seasons

Plants
Broccoli is a rich source of diverse bioactive compounds, but how their contents are influenced by different growing seasons and variations in broccoli head sizes remains elusive.
Lu Shi, Yahui Li, Menghua Lin, Ying Liang, Zhiyong Zhang   +4 more
doaj   +1 more source

Clinical and molecular evidence of the consumption of broccoli, glucoraphanin and sulforaphane in humans.

Nutricion hospitalaria, 2015
Introduction: Sulforaphane (SFN) is an isothiocyanate derived from glucoraphanin (GRA), which is found in great amounts especially in broccoli. Its consumption has been reported to be associated with a lower risk of myocardial infarction and cancer development.
Conzatti, Adriana, Fróes, Fernanda Carolina Telles da Silva, Perry, Ingrid Dalira Schweigert, Souza, Carolina Guerini de   +3 more
openaire   +3 more sources

Variation in broccoli cultivar phytochemical content under organic and conventional management systems: implications in breeding for nutrition.

PLoS ONE, 2014
Organic agriculture requires cultivars that can adapt to organic crop management systems without the use of synthetic pesticides as well as genotypes with improved nutritional value.
Erica N C Renaud, Edith T Lammerts van Bueren, James R Myers, Maria João Paulo, Fred A van Eeuwijk, Ning Zhu, John A Juvik   +6 more
doaj   +1 more source