Results 51 to 60 of about 1,963 (164)
Pharmaceuticals, 2022 Glucoraphanin (GRA) is a natural compound that has shown beneficial effects in chronic diseases and in central nervous system disorders. Moreover, GRA displayed antidepressant activity in preclinical models.
Paolo Tucci +8 more
doaj +1 more source
EFSA Journal, Volume 24, Issue 8, August 2026.Abstract Genetically modified RF3 Canola Quality (CQ) Brassica juncea was developed to confer tolerance to glufosinate‐based herbicides and to restore fertility in Barnase‐expressing plants. The RF3 event was originally developed in Brassica napus and has previously been assessed by EFSA in application EFSA‐GMO‐RX‐MS8‐RF3.
EFSA Panel on Genetically Modified Organisms (GMO) +30 more
wiley +1 more source
044 Selection for Floret Glucoraphanin Concentration Among Inbred Broccoli [PDF]
HortScience, 1999 Broccoli ( Brassica oleracea L. Italica Group) is a rich source of the aliphatic glucosinolate glucoraphanin. The glucoraphanin breakdown product, sulforaphane, has been shown to induce Phase II detoxication enzymes (e.g., Quinone Reductase) and has attracted attention as a potential ...
Mark W. Farnham +2 more
openaire +1 more source
Foods, 2021 There are no known physiological-based digestion models that depict glucoraphanin (GR) to sulforaphane (SR) conversion and subsequent absorption. The aim of this research was to make a physiological-based digestion model that includes SR formation, both ...
Quchat Shekarri, Matthijs Dekker
doaj +1 more source
Food Frontiers, Volume 7, Issue 4, July 2026.This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du +7 more
wiley +1 more source
International Journal of Molecular Sciences, 2022 Sarcopenia is a gradual and generalized skeletal muscle (SKM) syndrome, characterized by the impairment of muscle components and functionality. Hydrogen sulfide (H2S), endogenously formed within the body from the activity of cystathionine-γ-lyase (CSE), cystathionine- β-synthase (CBS), and mercaptopyruvate sulfurtransferase, is involved in SKM function.
Laura Micheli +10 more
openaire +4 more sources
Antioxidants, 2022 As the prevalence of inflammatory bowel diseases (IBD) rises, the etiology of IBD draws increasing attention. Glucoraphanin (GRP), enriched in cruciferous vegetables, is a precursor of sulforaphane, known to have anti-inflammatory and antioxidative ...
Qiyu Tian +5 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 7, July 2026.Sulforaphane modulates mTOR, Nrf2, NF‐κB, and AMPK/PGC‐1α pathways to protect skeletal muscle and enable precision‐medicine intervention in ICU‐acquired weakness, sarcopenia, and diabetic myopathy. ABSTRACT Sulforaphane (SFN), a bioactive isothiocyanate abundant in cruciferous vegetables, has attracted growing interest as a potential nutraceutical ...
Minru Zhao +8 more
wiley +1 more source
Bioaccessibility of glucoraphanin from broccoli using anin vitrogastrointestinal digestion model [PDF]
CyTA - Journal of Food, 2014 This study investigated the effect of cooking methods on the degradation of glucoraphanin (GR) in broccoli and the bioaccessibility of this compound through simulated gastrointestinal digestion. Broccoli was cooked using three different techniques: boiling, steaming and microwave cooking.
Cuomo, Valentina +4 more
openaire +2 more sources
Frontiers in Oncology, 2023 ObjectivesThis paper presents a systematic review aimed at assessing the therapeutic potential of sulforaphane (SFN) in the treatment of diverse cancer types.MethodsFollowing Cochrane guidelines for systematic reviews, we conducted an exhaustive search ...
Dana ElKhalifa +4 more
doaj +1 more source