Results 51 to 60 of about 2,817 (157)

The Challenges of Designing and Implementing Clinical Trials With Broccoli Sprouts… and Turning Evidence Into Public Health Action

open access: yesFrontiers in Nutrition, 2021
Broccoli sprouts are a convenient and rich source of the glucosinolate glucoraphanin, which can generate the chemopreventive agent sulforaphane through the catalytic actions of plant myrosinase or β-thioglucosidases in the gut microflora.
Jed W. Fahey   +5 more
doaj   +1 more source

sj-pdf-1-tor-10.1177_23978473211068834 – Supplemental Material for Toxicological assessment of truebroc® glucoraphanin-rich broccoli seed extract

open access: yes, 2022
Supplemental Material, sj-pdf-1-tor-10.1177_23978473211068834 for Toxicological assessment of truebroc® glucoraphanin-rich broccoli seed extract by Claire L Kruger, Jennifer Symonds and Dietrich Conze in Toxicology Research and ...
Jennifer Symonds (12043425)   +2 more
core   +1 more source

Exogenous Melatonin Promotes Glucoraphanin Biosynthesis by Mediating Glutathione in Hairy Roots of Broccoli (Brassica oleracea L. var. italica Planch)

open access: yesPlants, 2023
To investigate the mechanism of melatonin (MT)-mediated glutathione (GSH) in promoting glucoraphanin (GRA) and sulforaphane (SF) synthesis, the gene expression pattern and protein content of hairy broccoli roots under MT treatment were analyzed by a ...
Jinyu Bao   +9 more
doaj   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora   +8 more
wiley   +1 more source

Transport engineering as a strategy to realize rapeseed's potential as a protein‐rich food

open access: yesPest Management Science, Volume 82, Issue 11, Page 10534-10539, November 2026.
The heavily pesticide‐dependent rapeseed is an under‐utilized protein source for food owing to anti‐nutritional glucosinolates. Transport engineering technology may reduce glucosinolates in seeds while increasing defense in vegetative parts. Abstract Rapeseed is the world's second‐largest oilseed crop, and the low‐value press cake that remains after ...
Jakob Skytte Thorsen   +2 more
wiley   +1 more source

Seedling resistance and chemical defenses against Psylliodes chrysocephala: the roles of seed age and sinapinic acid in Sinapis alba and Brassica napus

open access: yesPest Management Science, Volume 82, Issue 11, Page 10727-10738, November 2026.
The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde   +4 more
wiley   +1 more source

Sulforaphane is superior than glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells

open access: yes, 2013
Glucoraphanin is the main glucosinolate found in broccoli and other cruciferous vegetables (Brassicaceae). The objective of the study was to evaluate whether glucoraphanin and its breakdown product sulforaphane, are potent modulators of various phase I ...
Abdull Razis, Ahmad Faizal   +1 more
core   +1 more source

Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective

open access: yesFrontiers in Pharmacology, 2018
Depression is one of the most common mood disorders with a high rate of relapse. Accumulating evidence suggests that the transcription factor Kelch-like erythroid cell-derived protein with CNC homology (ECH)-associated protein 1 (Keap1)-Nuclear factor ...
Kenji Hashimoto
doaj   +1 more source

Engineering of methionine chain elongation part of glucoraphanin pathway in E. coli

open access: yes, 2016
The methionine-derived glucosinolate glucoraphanin is associated with the health-promoting properties of broccoli. This has developed a strong interest in producing this compound in high amounts from a microbial source.
Halkier, Barbara Ann   +3 more
core   +1 more source

Variation of glucoraphanin and glucobrassicin: anticancer components in Brassica during processing [PDF]

open access: yes, 2013
Effects of cold storage and three common cooking practices, blanching, sauteing, and microwave cooking at different time intervals, on the content of glucosinolate (GSL) anticancer components in six Brassica vegetables were investigated.
Choi,Yun-Jong   +7 more
core   +1 more source

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