Results 41 to 50 of about 2,817 (157)

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases [PDF]

, 2021
COVID-19 is described in a clinical case involving a patient who proposed the hypothesis that Nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-interacting nutrients may help to prevent severe COVID-19 symptoms.
Czarlewski W., Bousquet J., Zuberbier T., Cristol J. -P., Reynes J., Blain H., Pizarro Lozano N., Mullol J., de la Torre R., Samolinski B., Valiulis A., Bedbrook A., Anto J. M., Fiocchi A., Cruz A. A., Haahtela T., Klimek L., Melen E., Kuna P., Iaccarino G., Le Moing V.   +20 more
core   +3 more sources

Sulforaphane as a potential modifier of calorie-induced inflammation: a double-blind, placebo-controlled, crossover trial

Frontiers in Nutrition, 2023
Background and aimsObservational data indicate that diets rich in fruits and vegetables have a positive effect on inflammatory status, improve metabolic resilience and may protect against the development of non-communicable diseases.
Hidde P. van Steenwijk, Anna Vinken, Frits H. M. van Osch, Frits H. M. van Osch, Herman Peppelenbos, Freddy J. Troost, Freddy J. Troost, Aalt Bast, Aalt Bast, Khrystyna O. Semen, Alie de Boer   +10 more
doaj   +1 more source

Prevention of Myc-Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane. [PDF]

Mol Carcinog
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Singh KB, Hahm ER, Jacobs BL, Singh SV.
europepmc   +2 more sources

Contrary to Red, Blue Monochromatic Light Improves the Bioactive Compound Content in Broccoli Sprouts

Agronomy, 2021
Broccoli sprouts are rich in health-promoting bioactive compounds. Their content depends on both cultivation light quality and temperature. However, these effects have been previously addressed in isolation.
Li Yang, Dimitrios Fanourakis, Georgios Tsaniklidis, Kun Li, Qichang Yang, Tao Li   +5 more
doaj   +1 more source

Effect of Glucoraphanin on the Abundance of Nrf2 Regulated Genes Within Circulating Small Extracellular Vesicles: A Pilot Dietary Intervention. [PDF]

Mol Nutr Food Res
Cruciferous vegetables, including broccoli, are associated with a reduced risk of age-related chronic diseases. Broccoli accumulates glucoraphanin, which is hydrolyzed to sulforaphane, an isothiocyanate, that activates antioxidant genes via nuclear ...
Mitra N, Vickers MH, Lithander FE, Artuyants A, Blenkiron C, Foster M, Phua HH, Pook C, Wang Z, Mithen RF, Ramzan F.   +10 more
europepmc   +2 more sources

Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice [PDF]

, 2017
Low-grade sustained inflammation links obesity to insulin resistance and nonalcoholic fatty liver disease (NAFLD). However, therapeutic approaches to improve systemic energy balance and chronic inflammation in obesity are limited.
Chiaki Takahashi, Nobuo Fuke, Liang Xu, Ryohei Umeda, Shuichi Kaneko, Yudai Aoki, Yinhua Ni, Naoto Nagata, Fen Zhuge, Yusuke Ushida, Mayumi Nagashimada, Tsuguhito Ota, Hiroyuki Suganuma, Susumu Kohno   +13 more
core   +1 more source

Characterisation of the Introgression of Brassica villosa Genome Into Broccoli to Enhance Methionine-Derived Glucosinolates and Associated Health Benefits

Frontiers in Plant Science, 2022
Broccoli cultivars that have enhanced accumulation of methionine-derived glucosinolates have been developed through the introgression of a novel allele of the MYB28 transcription factor from the wild species Brassica villosa.
Mikhaela Neequaye, Mikhaela Neequaye, Burkhard Steuernagel, Shikha Saha, Martin Trick, Perla Troncoso-Rey, Frans van den Bosch, Maria H. Traka, Lars Østergaard, Richard Mithen, Richard Mithen   +10 more
doaj   +1 more source

Thermosonication of Broccoli Florets Prior to Fermentation Increases Bioactive Components in Fermented Broccoli Puree

Fermentation, 2022
The aim of this study was to compare the effects of thermosonication (18 kHz at 60 °C for 7 min) pre-treatment with thermal treatment alone (60 °C for 7 min) of broccoli florets prior to pureeing and fermentation on selected bioactive components of ...
Sajad Shokri, Hema Jegasothy, Mya Myintzu Hliang, Mary Ann Augustin, Netsanet Shiferaw Terefe   +4 more
doaj   +1 more source

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

Molecules, 2019
There is robust epidemiological evidence for the beneficial effects of broccoli consumption on health, many of them clearly mediated by the isothiocyanate sulforaphane.
Yoko Yagishita, Jed W. Fahey, Albena T. Dinkova-Kostova, Thomas W. Kensler   +3 more
doaj   +1 more source

Effect of zinc fertilisation on yield and selected qualitative parameters of broccoli

Plant, Soil and Environment, 2017
Three treatments were used in two-year (2014-2015) field experiments with broccoli cv. Bejo 2914 F1: (1) untreated control; (2) Zn0.75 - Zinkuran SC as foliar fertiliser at the rate of 0.75 L/ha (375 g Zn/ha); (3) Zn1.50 - Zinkuran SC as foliar ...
Miroslav ŠLOSÁR, Ivana MEZEYOVÁ, Alžbeta HEGEDÜSOVÁ, Alena ANDREJIOVÁ, Peter KOVÁČIK, Tomáš LOŠÁK, Tomáš KOPTA, Anna J. KEUTGEN   +7 more
doaj   +1 more source