Results 31 to 40 of about 2,803 (180)

Transcriptome and Metabolome Analyses of Glucosinolate Biosynthesis-Related Genes in Different Organs of Broccoli (Brassica oleracea L. var. italica)

Applied Sciences, 2023
Broccoli (Brassica oleracea L. var. italica) is a globally popular vegetable because of its nutrient richness, especially its glucosinolates (GSLs). The content of GSLs in different organs of broccoli varies greatly.
Xiuling Tian, Hongju He, Xiaolu Yu, Yaqin Wang, Liping Hu, Bing Cheng, Yunhua Ding, Guangmin Liu   +7 more
doaj   +1 more source

Prevention of Myc-Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane. [PDF]

Mol Carcinog
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Singh KB, Hahm ER, Jacobs BL, Singh SV.
europepmc   +2 more sources

Steamed broccoli sprouts alleviate DSS-induced inflammation and retain gut microbial biogeography in mice

mSystems, 2023
Inflammatory bowel diseases (IBDs) are devastating conditions of the gastrointestinal tract with limited treatments, and dietary intervention may be effective and affordable for managing symptoms.
Johanna M. Holman, Louisa Colucci, Dorien Baudewyns, Joe Balkan, Timothy Hunt, Benjamin Hunt, Marissa Kinney, Lola Holcomb, Allesandra Stratigakis, Grace Chen, Peter L. Moses, Gary M. Mawe, Tao Zhang, Yanyan Li, Suzanne L. Ishaq   +14 more
doaj   +1 more source

Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease

mSystems, 2023
Crohn’s disease (CD) is a presentation of inflammatory bowel disease (IBD) that manifests in childhood and adolescence and involves chronic and severe enterocolitis, immune and gut microbial dysregulation, and other complications. Diet and gut-microbiota-
Lola Holcomb, Johanna M. Holman, Molly Hurd, Brigitte Lavoie, Louisa Colucci, Benjamin Hunt, Timothy Hunt, Marissa Kinney, Jahnavi Pathak, Gary M. Mawe, Peter L. Moses, Emma Perry, Allesandra Stratigakis, Tao Zhang, Grace Chen, Suzanne L. Ishaq, Yanyan Li   +16 more
doaj   +1 more source

Virtual Prediction of The Effect Phenolic And Glucosinolate Compounds In Broccoli (Brassica Oleracea) On Anti-aging As Stimulant Nrf-2

Journal of Experimental Life Science, 2020
Aging is caused by an imbalance between antioxidants and ROS. Nuclear Factor Erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates antioxidant genes. Under normal conditions, Nrf2 will bind keap1 and cause degradation of Nrf2. Nrf2
Viona Faiqoh Hikmawati, Fajar Mustika Alam, Jihan Shavira Ainnayah, Fatchiyah Fatchiyah   +3 more
doaj   +1 more source

Quantification and Diversity Analyses of Glucosinolates in 191 Broccoli Genotypes Highlight Valuable Genetic Resources for Molecular Breeding

Agronomy, 2023
Glucosinolates (GSLs), crucial secondary metabolites in cruciferous vegetables, hydrolyze upon consumption or mechanical damage, forming bioactive compounds with anti-cancer properties, such as glucoraphanin (GRA).
Meijia Yan, Chenxue Song, Shiwen Su, Junliang Li, Zhiwei Hu, Sue Lin, Huixi Zou, Zheng Tang, Xiufeng Yan   +8 more
doaj   +1 more source

Sulforaphane as a potential modifier of calorie-induced inflammation: a double-blind, placebo-controlled, crossover trial

Frontiers in Nutrition, 2023
Background and aimsObservational data indicate that diets rich in fruits and vegetables have a positive effect on inflammatory status, improve metabolic resilience and may protect against the development of non-communicable diseases.
Hidde P. van Steenwijk, Anna Vinken, Frits H. M. van Osch, Frits H. M. van Osch, Herman Peppelenbos, Freddy J. Troost, Freddy J. Troost, Aalt Bast, Aalt Bast, Khrystyna O. Semen, Alie de Boer   +10 more
doaj   +1 more source

Effect of Glucoraphanin on the Abundance of Nrf2 Regulated Genes Within Circulating Small Extracellular Vesicles: A Pilot Dietary Intervention. [PDF]

Mol Nutr Food Res
Cruciferous vegetables, including broccoli, are associated with a reduced risk of age-related chronic diseases. Broccoli accumulates glucoraphanin, which is hydrolyzed to sulforaphane, an isothiocyanate, that activates antioxidant genes via nuclear ...
Mitra N, Vickers MH, Lithander FE, Artuyants A, Blenkiron C, Foster M, Phua HH, Pook C, Wang Z, Mithen RF, Ramzan F.   +10 more
europepmc   +2 more sources

Contrary to Red, Blue Monochromatic Light Improves the Bioactive Compound Content in Broccoli Sprouts

Agronomy, 2021
Broccoli sprouts are rich in health-promoting bioactive compounds. Their content depends on both cultivation light quality and temperature. However, these effects have been previously addressed in isolation.
Li Yang, Dimitrios Fanourakis, Georgios Tsaniklidis, Kun Li, Qichang Yang, Tao Li   +5 more
doaj   +1 more source

Glucoraphanin Level in Broccoli Seed is Largely Determined by Genotype [PDF]

HortScience, 2005
Broccoli ( Brassica oleracea L., Italica Group) seed and resulting sprouts can contain high levels of glucoraphanin, a glucosinolate, which can be converted to sulforaphane, a compound with cancer protective and antioxidant properties. This observation has stimulated interest in broccoli seed
Mark W. Farnham, Katherine K. Stephenson, Jed W. Fahey   +2 more
openaire   +1 more source