Results 31 to 40 of about 3,475 (207)
Glucosinolate hydrolysis and bioavailability of resulting isothiocyanates: Focus on glucoraphanin
Journal of Functional Foods, 2014 There is a growing interest in the health benefits of broccoli. Sulforaphane, the major bioactive component in broccoli, is an unstable isothiocyanate stored in the plant as glucoraphanin. Myrosinase enzymes release sulforaphane when the plant is crushed. Extraction during supplement formulation or heat processing can destroy myrosinase.
Angelino D., Jeffery E.
openaire +4 more sources
Engineering of methionine chain elongation part of glucoraphanin pathway in E. coli
Metabolic Engineering, 2016 The methionine-derived glucosinolate glucoraphanin is associated with the health-promoting properties of broccoli. This has developed a strong interest in producing this compound in high amounts from a microbial source. Glucoraphanin synthesis starts with a five-gene chain elongation pathway that converts methionine to dihomo-methionine, which is ...
Mirza, Nadia Muhammad Akram +3 more
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Glucosinolate–Myrosinase Formulations for Adult Obesity: Towards Next Generation of Bioactive Therapies [PDF]
FoodsThe rising global prevalence of obesity and metabolic disorders calls for innovative dietary strategies that can modulate key enzymatic pathways involved in lipid and carbohydrate metabolism.
Concepción Medrano-Padial +4 more
doaj +2 more sources
Pharmaceuticals, 2022 Glucoraphanin (GRA) is a natural compound that has shown beneficial effects in chronic diseases and in central nervous system disorders. Moreover, GRA displayed antidepressant activity in preclinical models.
Paolo Tucci +8 more
doaj +2 more sources
Asian Pacific Journal of Cancer Prevention, 2013 Glucoraphanin is the main glucosinolate found in broccoli and other cruciferous vegetables (Brassicaceae). The objective of the study was to evaluate whether glucoraphanin and its breakdown product sulforaphane, are potent modulators of various phase I and phase II enzymes involved in carcinogen-metabolising enzyme systems in vitro.
Abdull Razis, Ahmad Faizal +1 more
openaire +4 more sources
Analytica Chimica Acta, 2010 Glucoraphanin, a glucosinolate, is found naturally in plants and is present in relatively high concentrations in broccoli. Glucosinolates have received much attention as studies have indicated that a diet rich in them may provide some protection from certain cancers.
Iris, Lee +2 more
openaire +3 more sources
Nutrients, 2022 Osteopenia and osteoporosis are among the most prevalent consequences of ageing, urging the promotion of healthy nutritional habits as a tool in preventing bone fractures.
L. Gambari +8 more
semanticscholar +2 more sources
Transcriptional changes in prostate of men on active surveillance after a 12-mo glucoraphanin-rich broccoli intervention—results from the Effect of Sulforaphane on prostate CAncer PrEvention (ESCAPE) randomized controlled trial [PDF]
American Journal of Clinical Nutrition, 2019 Background Epidemiological evidence suggests that consumption of cruciferous vegetables is associated with reduced risk of prostate cancer progression, largely attributed to the biological activity of glucosinolate degradation products, such as ...
M. Traka +18 more
semanticscholar +2 more sources
Effects of nanocarbon solution treatment on the nutrients and glucosinolate metabolism in broccoli
Food Chemistry: X, 2022 The effects of a nanocarbon solution on the nutrients, glucosinolate metabolism and glucoraphanin pathway in broccoli were investigated. Significant positive linear relationships were observed between the nanocarbon solution and total protein yield ...
Zhansheng Li +5 more
doaj +1 more source
Production of the Cancer-Preventive Glucoraphanin in Tobacco [PDF]
Molecular Plant, 2010 Epidemiological studies have demonstrated reduced risk of developing cancer upon consumption of diets rich in cruciferous vegetables. This chemoprevention has been largely attributed to the presence of the natural products glucosinolates, particularly the methionine-derived glucoraphanin from broccoli.
Mikkelsen, Michael Dalgaard +2 more
openaire +3 more sources