Results 121 to 130 of about 4,725 (241)

Can sulforaphane prevent the onset or slow the progression of osteoarthritis? [PDF]

, 2016
Osteoarthritis (OA) is a degenerative joint disease characterised in part by destruction of articular cartilage. There are currently no disease-modifying drugs to treat OA, with joint replacement the only treatment offered to patients at end-stage ...
Burrage, Cawston, Chen, Conaway, Dashwood, Davidson, Dinkova-Kostova, Fosang, Gasper, Goldring, Goldring, Green, Healy, Heiss, Jakubikova, Juge, Kim, Kong, McHughes, Richmond, Shane Anderson   +20 more
core   +1 more source

Taste and flavour perceptions of glucosinolates, isothiocyanates, and related compounds [PDF]

, 2018
Brassicaceae plants are renowned for their taste, aroma and trigeminal characteristics; predominantly bitter taste, sulfurous aroma and pungency. Compounds responsible for these sensations include the glucosinolates (GSLs) and their hydrolysis products ...
Abe, Agerbirk, Agneta, Agrawal, Baik, Beaver, Behrens, Bell, Bell, Bell, Bell, Bell, Bennett, Bennett, Bonnema, Buck, Cartea, Cerny, Chen, Chin, Chin, Coogan, D'Antuono, D'Auria, Depree, Dinkova-Kostova, Doorn, Drewnowski, Elmore, Elmore, Engel, Fahey, Fenwick, Fenwick, Fowke, Frandsen, Frank, Freeman, Fukuda, Ghawi, Ghawi, Giacoppo, Halkier, Hanschen, Hanschen, Hansen, Hansen, Hasin, Hayes, Hayes, Holst, Hufnagel, Ishida, Jaeger, Jakubikova, Jin, Jirovetz, Jones, Jordt, Kato, Keller, Khataan, Kim, Kirimura, Kubec, Kuchernig, Levine, Lindsay, Ludikhuyze, Matusheski, Matusheski, McRae, Melchini, Mennella, Methven, Meyerhof, Nishimura, Okunade, Padilla, Palaniswamy, Palermo, Park, Parker, Pasini, Pence, Possenti, Prescott, Raffo, Rangkadilok, Reed, Ridgway, Sandell, Sansom, Sarkar, Schonhof, Shapiro, Shen, Siegmund, Steinmetz, Stoewsand, Sultana, Sultana, Suzuki, Swanston, Traka, Traka, Voutsina, Wills, Wold, Wu, Zabaras, Zhao   +111 more
core   +1 more source

Identification and Biological Characterization of a Novel NRF2 Activator Molecule Released From the Membranes of Heat‐Treated Bifidobacterium breve NCC 2950

Molecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
We have shed light on the mode of action behind the postbiotic form of Bifidobacterium breve NCC 2950. Heat treatment of this strain at 90°C leads to the production of 4‐oxo‐2‐pentenoic acid (OPA), which activates NRF2 host response, improving oxidative stress resistance and decreasing inflammation. ABSTRACT Postbiotics are defined as a “preparation of
Francis Foata, Stéphane Duboux, Sébastien Herzig, Federico Sizzano, Jonathan Thevenet, Philippe Guy, Serge Rezzi, Sylviane Métairon, Bertrand Bourqui, Ivan Montoliu, Annick Mercenier, Nabil Bosco   +11 more
wiley   +1 more source

Systematic Study of the Content of Phytochemicals in Fresh and Fresh-Cut Vegetables [PDF]

, 2015
Vegetables and fruits have beneficial properties for human health, because of the presence of phytochemicals, but their concentration can fluctuate throughout the year. A systematic study of the phytochemical content in tomato, eggplant, carrot, broccoli
Antonia Garrido Frenich, José Luis, Martínez Vidal, María Isabel Alarcón-flores, Roberto Romero-gonzález   +4 more
core   +4 more sources

Sulforaphane-enriched extracts from glucoraphanin-rich broccoli exert antimicrobial activity against gut pathogens in vitro and innovative cooking methods increase in vivo intestinal delivery of sulforaphane

European Journal of Nutrition, 2020
Purpose Studies on broccoli ( Brassica oleracea var. italica ) indicate beneficial effects against a range of chronic diseases, commonly attributed to their bioactive phytochemicals.
Salah Abukhabta, Sameer Khalil Ghawi, K. Karatzas, D. Charalampopoulos, G. McDougall, J. Will Allwood, S. Verrall, Siobhán Lavery, C. Latimer, L. K. Pourshahidi, R. Lawther, G. O’Connor, I. Rowland, Chris I. R. Gill   +13 more
semanticscholar   +1 more source

Micellar electrokinetic capillary chromatography—Synchronous monitoring of substrate and products in the myrosinase catalysed hydrolysis of glucosinolates [PDF]

, 2006
A micellar electrokinetic capillary chromatography (MECC) method has been developed for monitoring the myrosinase catalysed hydrolysis of 2-hydroxy substituted glucosinolates and the simultaneous formation of the corresponding degradation products ...
Bellostas, Natalia, Sorensen, Hilmer, Sorensen, Jens Christian   +2 more
core   +1 more source

Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The VEgetableS for vaScular hEaLth (VESSEL) study

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4300-4310, August 2025.
Abstract Aims Higher cruciferous vegetable (e.g., broccoli) intake is associated with lower risk of type 2 diabetes and cardiovascular disease, but limited causal evidence exists. We investigated if cruciferous vegetable intake improved glycaemic control compared to root/squash vegetables in non‐diabetic adults with elevated blood pressure.
Emma L. Connolly, Alex H. Liu, Richard J. Woodman, Armaghan Shafaei, Lisa G. Wood, Richard Mithen, Anthony P. James, Carl J. Schultz, Seng Khee Gan, Catherine P. Bondonno, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst   +12 more
wiley   +1 more source

Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky, Mohammed E. Abo‐El Fetoh, Safaa A. Faheem, Abdullah F. Radwan, Mariam H. Fawzy, Aya M. Mustafa, Mohamed A. Said, Daniela Calina, Javad Sharifi‐Rad, William C. Cho   +9 more
wiley   +1 more source

Supplementation of the diet by exogenous myrosinase via mustard seeds to increase the bioavailability of sulforaphane in healthy human subjects after the consumption of cooked broccoli [PDF]

, 2018
Broccoli contains the glucosinolate glucoraphanin which, in the presence of myrosinase, can hydrolyse to the isothiocyanate sulforaphane, reported to have anti-carcinogenic activity. However, the myrosinase enzyme is denatured on cooking.
Armah, Bones, Clarke, Conaway, Cramer, Dekker, Dosz, Eylen, Eylen, Eylen, Ghawi, Kassahun, Keck, Lampe, Ludikhuyze, Matusheski, Matusheski, Murashima, Myzak, Oerlemans, Okunade, Perez, Radhika, Rouzaud, Rouzaud, Rungapamestry, Shapiro, Song, Verkerk, Vermeulen, Williams, Wu, Yen, Zhang   +33 more
core   +1 more source

The influence of phytochemical composition and resulting sensory attributes on preference for salad rocket (Eruca sativa) accessions by consumers of varying TAS2R38 diplotype [PDF]

, 2016
Seven accessions of Eruca sativa (“salad rocket”) were subjected to a randomised consumer assessment. Liking of appearance and taste attributes were analysed, as well as perceptions of bitterness, hotness, pepperiness and sweetness.
Amodio, Bartoshuk, Bell, Bell, Bell, Bennett, Buttery, Carol Wagstaff, Carpenter, D’Antuono, Engel, Garcia-Bailo, Hall, Hayes, Hayes, Hirai, Hough, Ishida, Jin, Le Nevé, Lisa Methven, Lokke, Luke Bell, Martinez-Sanchez, Mennella, Meyerhof, Nelson, Pasini, Reed, Schonhof, Shen, Tepper, Tepper, Traka, Wooding   +34 more
core   +1 more source