Anti-inflammatory activity of synthetic and natural glucoraphanin [PDF]
Journal of the Serbian Chemical Society, 2019 Glucoraphanin is one of the best known glucosinolates because of its health benefits. The compound is known to eliminate carcinogens in tissue and hence is frequently studied for its cancer preventative properties. In this work, the total synthesis of α-
Vo Quan V. +4 more
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Optimization of engineered production of the glucoraphanin precursor dihomo-methionine in Nicotiana benthamiana [PDF]
Frontiers in Bioengineering and Biotechnology, 2016 Glucosinolates are natural products characteristic of the Brassicales order which include vegetables such as cabbages and the model plant Arabidopsis thaliana.
Christoph eCrocoll +7 more
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Genetic regulation of glucoraphanin accumulation in Beneforté® broccoli [PDF]
New Phytologist, 2013 Diets rich in broccoli (Brassica oleracea var italica) have been associated with maintenance of cardiovascular health and reduction in risk of cancer. These health benefits have been attributed to glucoraphanin that specifically accumulates in broccoli ...
Anon +17 more
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Reduction of the sulfoxide in glucoraphanin and sulforaphane by E. coli VL11 and BL21 (DE3) [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2016 Sulfoxide reductase activity of two Escherichia coli strains VL11 from human feces and BL21(DE3) from a molecular cloning host was expressed upon glucoraphanin induction for 16 hrs at 37°C under aerobic conditions.
Vijitra Luang-In +1 more
doaj +3 more sources
Factors Influencing Glucoraphanin and Sulforaphane Formation in Brassica Plants: A Review
Journal of Integrative Agriculture, 2012 Sulforaphane is a type of sulfur-containing isothiocyanates hydrolyzed from glucosinolates by myrosinase found in Brassica plants. Sulforaphane is a naturally occurring inducer of phase II enzymes in human and animal bodies to detoxify cancer-causing ...
Zhen-xin GU, Qiang-hui GUO, Ying-juan GU
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Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: evidence from randomised controlled trials [PDF]
Molecular Nutrition & Food Research, 2015 Cruciferous-rich diets have been associated with reduction in plasma LDL-cholesterol (LDL-C), which may be due to the action of isothiocyanates derived from glucosinolates that accumulate in these vegetables.
Armah, Charlotte N. +9 more
core +9 more sources
The Effect of Broccoli Glucoraphanin Supplementation on Ameliorating High‐Fat‐Diet‐Induced Obesity through the Gut Microbiome and Metabolome Interface [PDF]
Molecular Nutrition & Food ResearchObesity and its metabolic comorbidities pose a major global challenge for public health. Glucoraphanin (GRN) is a natural bioactive compound enriched in broccoli that is known to have potential health benefits against various human chronic diseases.
Taiwo Bankole +6 more
semanticscholar +3 more sources
Large insertion in radish GRS1 enhances glucoraphanin content in intergeneric hybrids, Raphanobrassica (Raphanus sativus L. x Brassica oleracea var. acephala) [PDF]
Frontiers in Plant Science, 2023 Glucosinolates (GSLs), precursors of isothiocyanates (ITCs), are present in Brassicaceae plants have been found to have health benefits. Sulforaphane (4-(methylsulfinyl)butyl ITC) is an ITC stored in the form of 4-(methylsulfinyl)butyl GSL (glucoraphanin,
R. Endo +5 more
semanticscholar +2 more sources
Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase. [PDF]
PLoS ONE, 2015 Glucoraphanin from broccoli and its sprouts and seeds is a water soluble and relatively inert precursor of sulforaphane, the reactive isothiocyanate that potently inhibits neoplastic cellular processes and prevents a number of disease states ...
Jed W Fahey +5 more
doaj +4 more sources
Glucoraphanin Increases Intracellular Hydrogen Sulfide (H2S) Levels and Stimulates Osteogenic Differentiation in Human Mesenchymal Stromal Cell [PDF]
Nutrients, 2022 Osteopenia and osteoporosis are among the most prevalent consequences of ageing, urging the promotion of healthy nutritional habits as a tool in preventing bone fractures.
L. Gambari +8 more
semanticscholar +2 more sources