Results 201 to 210 of about 4,001 (226)
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Zeitschrift für Phytotherapie, 2023
ZusammenfassungAls eine vielversprechende Quelle für bioaktive pflanzliche Sekundärstoffe gelten Keimsprossen von Kreuzblütlerpflanzen (Familie: Brassicaceae). Vor allem das in Brokkolisprossen in höheren Konzentrationen vorkommende Glucoraphanin ist als bioaktiver Naturstoff von
Matthias Lechtenberg +2 more
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ZusammenfassungAls eine vielversprechende Quelle für bioaktive pflanzliche Sekundärstoffe gelten Keimsprossen von Kreuzblütlerpflanzen (Familie: Brassicaceae). Vor allem das in Brokkolisprossen in höheren Konzentrationen vorkommende Glucoraphanin ist als bioaktiver Naturstoff von
Matthias Lechtenberg +2 more
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The effect of processing and cooking on glucoraphanin and sulforaphane in brassica vegetables
Food Chemistry, 2021Brassica vegetables are widely consumed mostly after processing and cooking. These processing and cooking methods not only can affect the taste, texture, flavor and nutrients of these vegetables, but also influence the levels of some important bioactive compounds, such as glucosinolates (GLSs).
Xinyi Pang, Shuhua Tian, Qiaobin Hu
exaly +3 more sources
The Metabolic Fate of Purified Glucoraphanin in F344 Rats
Journal of Agricultural and Food Chemistry, 2007Dietary broccoli is commonly eaten cooked, exposing individuals to intact glucoraphanin rather than to its hydrolysis product, the anticarcinogenic isothiocyanate sulforaphane, since cooking destroys the hydrolyzing enzyme myrosinase. There is little information on the absorption and metabolism of glucoraphanin, due partly to the lack of purified ...
Radha M, Bheemreddy +1 more
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Food Chemistry, 2020
The effect of postharvest melatonin treatment on sulforaphane production of fresh-cut broccoli at 4℃ during storage was investigated in this study. Florets treated with 100 μM melatonin exhibited higher contents of total glucosinolates and sulforaphane. Glucoraphanin content was significantly increased after melatonin treatment, and which was explained
Li-Yang Wei, Changhong Liu, Lei Zheng
exaly +3 more sources
The effect of postharvest melatonin treatment on sulforaphane production of fresh-cut broccoli at 4℃ during storage was investigated in this study. Florets treated with 100 μM melatonin exhibited higher contents of total glucosinolates and sulforaphane. Glucoraphanin content was significantly increased after melatonin treatment, and which was explained
Li-Yang Wei, Changhong Liu, Lei Zheng
exaly +3 more sources
A total synthesis of ( R , S ) S -glucoraphanin
Tetrahedron, 2013Abstract A total synthesis of (R,S)S-glucoraphanin (GRP) has been completed by a novel, simple and convenient method in high overall yield (17% over seven steps). The study describes a method for the synthesis of natural and unnatural (methylsulfinyl)alkyl glucosinolates (GLs) and also opens useful pathways to synthesize GRP as well as other sulfinyl
Quan V. Vo +3 more
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Glucoraphanin and sulforaphane evolution during juice preparation from broccoli sprouts
Food Chemistry, 2018Broccoli sprouts are considered functional food as they are naturally enriched in glucoraphanin (GR) that is the biological precursor of the anticancer compound sulforaphane (SFN). Due to its health promoting value, also broccoli sprout juice is becoming very popular.
Cristiano Bello +4 more
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The synthesis of isotopically labelled glucoraphanin for metabolic studies
Tetrahedron Letters, 2007Abstract The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10- 13 C,11,12- 2 H 5 ]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself.
John J. Morrison, Nigel P. Botting
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Further Optimization of Heterologous Glucoraphanin Biosynthesis Through Co‐Expression Analysis
The FASEB Journal, 2020It is estimated that 38.4% of adults in the United States will be diagnosed with cancer (National Cancer Institute). With this high rate of incidence, the exploration of new options for cancer prevention and treatment is of high importance.
Roxanna Pignolet +3 more
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Engineering of methionine chain elongation part of glucoraphanin pathway in E. coli
Metabolic Engineering, 2016The methionine-derived glucosinolate glucoraphanin is associated with the health-promoting properties of broccoli. This has developed a strong interest in producing this compound in high amounts from a microbial source. Glucoraphanin synthesis starts with a five-gene chain elongation pathway that converts methionine to dihomo-methionine, which is ...
Mirza, Nadia Muhammad Akram +3 more
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Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin
Food and Chemical Toxicology, 2008The anti-carcinogenic effects of broccoli have been attributed to sulforaphane, the hydrolysis product of glucoraphanin (GRP). Here we determined if purified GRP, in the absence of the plant-derived hydrolyzing enzyme myrosinase, could affect pulmonary and hepatic ethoxyresorufin O-deethylase (EROD) and/or NAD(P)H-quinone oxidoreductase 1 (NQO1 ...
R-H, Lai +4 more
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