Variation in broccoli cultivar phytochemical content under organic and conventional management systems: implications in breeding for nutrition. [PDF]
PLoS ONE, 2014 Organic agriculture requires cultivars that can adapt to organic crop management systems without the use of synthetic pesticides as well as genotypes with improved nutritional value.
Erica N C Renaud +6 more
doaj +3 more sources
Redox BiologyIntestinal permeabilization is central to the pathophysiology of chronic gut inflammation. This study investigated the efficacy of glucoraphanin (GR), prevalent in cruciferous vegetables, particularly broccoli, and its derivative sulforaphane (SF), in inhibiting tumor necrosis factor alpha (TNFα)-induced Caco-2 cell monolayers inflammation and ...
Wei Zhu +3 more
semanticscholar +7 more sources
Glucosinolate–Myrosinase Formulations for Adult Obesity: Towards Next Generation of Bioactive Therapies [PDF]
FoodsThe rising global prevalence of obesity and metabolic disorders calls for innovative dietary strategies that can modulate key enzymatic pathways involved in lipid and carbohydrate metabolism.
Concepción Medrano-Padial +4 more
doaj +2 more sources
Bioactivated Glucoraphanin Modulates Genes Involved in Necroptosis on Motor-Neuron-like Nsc-34: A Transcriptomic Study [PDF]
AntioxidantsResearch on bioactive compounds has grown recently due to their health benefits and limited adverse effects, particularly in reducing the risk of chronic diseases, including neurodegenerative conditions.
Aurelio Minuti +7 more
semanticscholar +2 more sources
Antioxidants, 2022 As the prevalence of inflammatory bowel diseases (IBD) rises, the etiology of IBD draws increasing attention. Glucoraphanin (GRP), enriched in cruciferous vegetables, is a precursor of sulforaphane, known to have anti-inflammatory and antioxidative ...
Qiyu Tian +5 more
doaj +2 more sources
Enriching Glucoraphanin in Brassica rapa Through Replacement of BrAOP2.2/BrAOP2.3 with Non-functional Genes [PDF]
Frontiers in Plant Science, 2017 Sulforaphane, the hydrolytic product of glucoraphanin glucosinolate, is a potent anticarcinogen that reduces the risk of several human cancers. However, in most B. rapa vegetables, glucoraphanin is undetectable or only present in trace amounts, since the
Zhiyuan Liu +8 more
doaj +3 more sources
Application of Tryptophan and Methionine in Broccoli Seedlings Enhances Formation of Anticancer Compounds Sulforaphane and Indole-3-Carbinol and Promotes Growth [PDF]
FoodsBroccoli is a popular cruciferous vegetable that is well known for its abundant health-promoting biochemicals. The most important of these beneficial biochemicals are glucosinolates, including glucoraphanin and glucobrassicin.
Rui Li +3 more
doaj +2 more sources
A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation [PDF]
Diabetology International, 2023 S. Promsuwan +5 more
semanticscholar +2 more sources
Neuropsychopharmacology Reports, 2020 Aim Epidemiological data suggest that maternal immune activation (MIA) plays a role in the etiology of neuropsychiatric disorders including autism spectrum disorder (ASD) and schizophrenia. However, there is no prophylactic nutrition that can prevent the
Yuko Fujita +6 more
doaj +2 more sources
Profiling the Bioactive Compounds in Broccoli Heads with Varying Organ Sizes and Growing Seasons [PDF]
PlantsBroccoli is a rich source of diverse bioactive compounds, but how their contents are influenced by different growing seasons and variations in broccoli head sizes remains elusive.
Lu Shi +4 more
doaj +2 more sources