Results 51 to 60 of about 3,865 (217)

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L., Diggins, Eileen, Dinkova-Kostova, Albena, Fahey, Jed W., Liu, Hua, Singh, Kanwaljit, Stephenson, Katherine K., Zimmerman, Andrew W.   +7 more
core   +3 more sources

The effect of chewing on oral glucoraphanin hydrolysis in raw and steamed broccoli

Journal of Functional Foods, 2018
Chewing disrupts broccoli cells, and myrosinase can effectively hydrolyze the glucosinolate glucoraphanin into the biological active sulforaphane. The influence of chewing time and steaming time on glucoraphanin hydrolysis as well as sulforaphane and sulforaphane nitrile formation in broccoli was studied.To study the effect of chewing time on ...
Irmela Sarvan, Michelle van der Klauw, Teresa Oliviero, Matthijs Dekker, Ruud Verkerk   +4 more
openalex   +3 more sources

Steamed broccoli sprouts alleviate DSS-induced inflammation and retain gut microbial biogeography in mice

mSystems, 2023
Inflammatory bowel diseases (IBDs) are devastating conditions of the gastrointestinal tract with limited treatments, and dietary intervention may be effective and affordable for managing symptoms.
Johanna M. Holman, Louisa Colucci, Dorien Baudewyns, Joe Balkan, Timothy Hunt, Benjamin Hunt, Marissa Kinney, Lola Holcomb, Allesandra Stratigakis, Grace Chen, Peter L. Moses, Gary M. Mawe, Tao Zhang, Yanyan Li, Suzanne L. Ishaq   +14 more
doaj   +1 more source

Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease

mSystems, 2023
Crohn’s disease (CD) is a presentation of inflammatory bowel disease (IBD) that manifests in childhood and adolescence and involves chronic and severe enterocolitis, immune and gut microbial dysregulation, and other complications. Diet and gut-microbiota-
Lola Holcomb, Johanna M. Holman, Molly Hurd, Brigitte Lavoie, Louisa Colucci, Benjamin Hunt, Timothy Hunt, Marissa Kinney, Jahnavi Pathak, Gary M. Mawe, Peter L. Moses, Emma Perry, Allesandra Stratigakis, Tao Zhang, Grace Chen, Suzanne L. Ishaq, Yanyan Li   +16 more
doaj   +1 more source

Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]

, 2018
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco, Artés Hernández, Francisco de Asís, Collado Marín, Elena, Martínez Hernández, Ginés Benito, Venzke Klug, Tâmmila   +4 more
core   +2 more sources

Variation and Distribution of Glucosinolates in 42 Cultivars of Brassica oleracea Vegetable Crops [PDF]

, 2010
Brassica vegetables are known to contain glucosinolates that are precursors for bioactive compounds like isothiocyanates that have been shown to play an important role in human health. This study reports the results of a screening of 11 Brassica oleracea
Dekker, M., Tebbenhoff, S., Verkerk, R.
core   +3 more sources

Thermosonication of Broccoli Florets Prior to Fermentation Increases Bioactive Components in Fermented Broccoli Puree

Fermentation, 2022
The aim of this study was to compare the effects of thermosonication (18 kHz at 60 °C for 7 min) pre-treatment with thermal treatment alone (60 °C for 7 min) of broccoli florets prior to pureeing and fermentation on selected bioactive components of ...
Sajad Shokri, Hema Jegasothy, Mya Myintzu Hliang, Mary Ann Augustin, Netsanet Shiferaw Terefe   +4 more
doaj   +1 more source

Growth temperature influences postharvest glucosinolate concentrations and hydrolysis product formation in first and second cuts of rocket salad [PDF]

, 2020
Rocket salad species (Diplotaxis tenuifolia and Eruca sativa; also known as E. vesicaria) are known for their high concentrations of health-related isothiocyanates, which are derived from secondary metabolites called glucosinolates.
Bell, Luke, Jasper, Jake, Wagstaff, Carol   +2 more
core   +1 more source

Virtual Prediction of The Effect Phenolic And Glucosinolate Compounds In Broccoli (Brassica Oleracea) On Anti-aging As Stimulant Nrf-2

Journal of Experimental Life Science, 2020
Aging is caused by an imbalance between antioxidants and ROS. Nuclear Factor Erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates antioxidant genes. Under normal conditions, Nrf2 will bind keap1 and cause degradation of Nrf2. Nrf2
Viona Faiqoh Hikmawati, Fajar Mustika Alam, Jihan Shavira Ainnayah, Fatchiyah Fatchiyah   +3 more
doaj   +1 more source

The Challenges of Designing and Implementing Clinical Trials With Broccoli Sprouts… and Turning Evidence Into Public Health Action

Frontiers in Nutrition, 2021
Broccoli sprouts are a convenient and rich source of the glucosinolate glucoraphanin, which can generate the chemopreventive agent sulforaphane through the catalytic actions of plant myrosinase or β-thioglucosidases in the gut microflora.
Jed W. Fahey, Jed W. Fahey, Jed W. Fahey, Jed W. Fahey, Thomas W. Kensler, Thomas W. Kensler   +5 more
doaj   +1 more source