Results 61 to 70 of about 4,725 (241)

Selenium Biofortification in Radish Enhances Nutritional Quality via Accumulation of Methyl-Selenocysteine and Promotion of Transcripts and Metabolites Related to Glucosinolates, Phenolics, and Amino Acids [PDF]

, 2016
Two selenium (Se) fertilization methods were tested for their effects on levels of anticarcinogenic selenocompounds in radish (Raphanus sativus), as well as other nutraceuticals.
Annarita Trentin, Chiara Berto, Elizabeth Pilon-Smits, Mario Malagoli, Michela Schiavon, Michela Schiavon, Paolo Sambo, Stefano Dall'aqua   +7 more
core   +3 more sources

Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS-induced colitis via intestinal barrier protection and gut microbiota modulation in mice.

The Journal of the Science of Food and Agriculture, 2022
BACKGROUND Broccoli has received widespread attention because of its anti-inflammatory and antioxidant effects. The present study aimed to explore the composition of broccoli seed extract (BSE) and its effect on colitis induced by dextran sulfate sodium (
Jiaying Wu, Weiling Guo, Shumao Cui, Xin Tang, Qiuxiang Zhang, Wenwei Lu, Yan Jin, Jianxin Zhao, Bingyong Mao, Wei Chen   +9 more
semanticscholar   +1 more source

Protective Activity of Broccoli Sprout Juice in a Human Intestinal Cell Model of Gut Inflammation [PDF]

, 2016
Benefits to health from a high consumption of fruits and vegetables are well established and have been attributed to bioactive secondary metabolites present in edible plants.
Baima, Simona, Ferruzza, Simonetta, Giusti, Anna Maria, Maldini, Mariateresa, Mattivi, Fulvio, Moneta, Elisabetta, Morelli, Giorgio, Murgia, Chiara, Nardini, Mirella, Natella, Fausta, Ranaldi, Giulia, Rossi, Carlotta, Sambuy, Yula, Scaccini, Cristina, Trošt, Kajetan   +14 more
core   +3 more sources

Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance [PDF]

Adipocyte, 2018
Obesity is a low-grade sustained inflammatory state that causes oxidative stress in different metabolic tissues, which leads to insulin resistance and nonalcoholic fatty liver disease (NAFLD). Particularly, obesity-induced metabolic endotoxemia plays an important role in the pathogenesis of insulin resistance and inflammation.
Liang Xu, Naoto Nagata, Tsuguhito Ota
openaire   +2 more sources

Direct quantitation of glucoraphanin in dog and rat plasma by LC–MS/MS [PDF]

Journal of Pharmaceutical and Biomedical Analysis, 2010
A rapid method to quantify levels of the beta-thioglycoside N-hydroxyl sulfate, glucoraphanin, in dog and rat plasma to support pre-clinical toxicological and pharmacological studies has been developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Michael Cwik, Huaping Wu, Miguel Muzzio, David L. McCormick, Izet M. Kapetanović   +4 more
openalex   +4 more sources

Molecular Cloning, Expression Pattern and Genotypic Effects on Glucoraphanin Biosynthetic Related Genes in Chinese Kale (Brassica oleracea var. alboglabra Bailey)

Molecules, 2015
Glucoraphanin is a plant secondary metabolite that is involved in plant defense and imparts health-promoting properties to cruciferous vegetables. In this study, three genes involved in glucoraphanin metabolism, branched-chain aminotransferase 4 (BCAT4),
Ling Yin, Changming Chen, Guoju Chen, Bihao Cao, Jianjun Lei   +4 more
doaj   +1 more source

Exogenous Selenium Treatment Promotes Glucosinolate and Glucoraphanin Accumulation in Broccoli by Activating Their Biosynthesis and Transport Pathways

Applied Sciences, 2022
Supplementation using selenium (Se) on plants is an effective and widely used approach. It can not only be converted to more Se rich compounds but promote the accumulation of glucosinolates (GSLs) with anti-carcinogenic properties. However, the molecular
Qi Wu, Junwei Wang, Huiping Huang, Shuxiang Mao, Qiuyu Wu, Ke Huang   +5 more
semanticscholar   +1 more source

Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds

Molecules, 2014
Dietary R-sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. Furthermore, sulforaphane is currently being used in clinical trials to assess its effects against different tumour processes. This study reports an efficient preparation of
Gina Rosalinda De Nicola, Patrick Rollin, Emanuela Mazzon, Renato Iori   +3 more
doaj   +1 more source

Quantification and Diversity Analyses of Glucosinolates in 191 Broccoli Genotypes Highlight Valuable Genetic Resources for Molecular Breeding

Agronomy, 2023
Glucosinolates (GSLs), crucial secondary metabolites in cruciferous vegetables, hydrolyze upon consumption or mechanical damage, forming bioactive compounds with anti-cancer properties, such as glucoraphanin (GRA).
Meijia Yan, Chenxue Song, Shiwen Su, Junliang Li, Zhiwei Hu, Sue Lin, Huixi Zou, Zheng Tang, Xiufeng Yan   +8 more
doaj   +1 more source

Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue [PDF]

, 2019
Scope: Observational studies have associated consumption of cruciferous vegetables with reduced risk of prostate cancer. This effect has been associated with the degradation products of glucosinolates—thioglycosides that accumulate within crucifers.
Ball, Richard Y., Beasy, Gemma, Coode-Bate, Jack, Dainty, Jack R., Maicha, Jean Bapiste, Melchini, Antonietta, Mills, Robert D., Mithen, Richard F., Needs, Paul W., Saha, Shikha, Sivapalan, Tharsini, Traka, Maria H.   +11 more
core   +1 more source