Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention [PDF]
The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation.
A Arlt +91 more
core +2 more sources
Broccoli sprouts are rich in health-promoting bioactive compounds. Their content depends on both cultivation light quality and temperature. However, these effects have been previously addressed in isolation.
Li Yang +5 more
doaj +1 more source
Effects of selenium biofortification on crop nutritional quality [PDF]
Selenium (Se) at very low doses has crucial functions in humans and animals. Since plants represent the main dietary source of this element, Se-containing crops may be used as a means to deliver Se to consumers (biofortification). Several strategies have
Dall'Acqua, Stefano +3 more
core +1 more source
Direct quantitation of glucoraphanin in dog and rat plasma by LC–MS/MS [PDF]
A rapid method to quantify levels of the beta-thioglycoside N-hydroxyl sulfate, glucoraphanin, in dog and rat plasma to support pre-clinical toxicological and pharmacological studies has been developed using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Michael J, Cwik +4 more
openaire +2 more sources
Glucosinolates (GSLs), crucial secondary metabolites in cruciferous vegetables, hydrolyze upon consumption or mechanical damage, forming bioactive compounds with anti-cancer properties, such as glucoraphanin (GRA).
Meijia Yan +8 more
doaj +1 more source
KEAP1 and done? Targeting the NRF2 pathway with sulforaphane:Targeting the NRF2 Pathway with Sulforaphane [PDF]
Background: Since the re-discovery of sulforaphane in 1992 and the recognition of the bioactivity of this phytochemical, many studies have examined its mode of action in cells, animals and humans.
Dinkova-Kostova, Albena T. +3 more
core +2 more sources
Synthesis and Evaluation of Pseudoglucosinolates Releasing Isothiocyanates in the Presence of Azoreductases. [PDF]
An expansion of the concept of pseudoglucosinolates (psGSLs) is reported introducing the first azoreductase‐responsive psGSL‐based probe releasing an isothiocyanate under simultaneous fluorescence turn‐on in the presence of AzoR, an azoreductase from Escherichia coli.
Chakrabarti A +13 more
europepmc +2 more sources
Decontamination of Listeria innocua from fresh-cut broccoli using UV-C applied in water or peroxyacetic acid, and dry-pulsed light [PDF]
The efficacy of two irradiation technologies: Ultraviolet-C light (UV-C), applied in water or in diluted peroxyacetic acid, and dry-pulsed light (PL) for the inactivation and growth inhibition of Listeria innocua in fresh-cut broccoli were evaluated ...
Abadias i Sero, Mª Isabel +6 more
core +3 more sources
Similarity of bioactivity between purified and semipurified glucoraphanin
The anti‐carcinogenic effects of cruciferous vegetables have been attributed to the hydrolysis products of glucosinolates; the primary glucosinolate in broccoli is glucoraphanin (GP). In this study, the goal was to determine if purified GP, in the absence of the plant‐derived hydrolyzing enzyme myrosinase, could affect pulmonary or hepatic ...
Ren‐Hau Lai, Elizabeth H. Jeffery
openaire +1 more source
Effect of zinc fertilisation on yield and selected qualitative parameters of broccoli
Three treatments were used in two-year (2014-2015) field experiments with broccoli cv. Bejo 2914 F1: (1) untreated control; (2) Zn0.75 - Zinkuran SC as foliar fertiliser at the rate of 0.75 L/ha (375 g Zn/ha); (3) Zn1.50 - Zinkuran SC as foliar ...
Miroslav ŠLOSÁR +7 more
doaj +1 more source

