Results 131 to 140 of about 110,124 (289)

Realizing the promise of ‘La Dolce Vita’ via chemical biology: glycan‐motif editing of sLeX for precision cancer therapeutics

open access: yesThe FEBS Journal, EarlyView.
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley   +1 more source

The gut‐microbiota‐brain axis: Focus on gut steroids

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract There are over 1000 varieties of steroids that have been reported in nature, including the endogenous sex steroid hormones (i.e., progesterone, testosterone, and 17β‐estradiol) and corticosteroids which are mainly synthesized by gonads and adrenals, respectively.
Silvia Diviccaro   +4 more
wiley   +1 more source

Analysis of the gut microbiome in sled dogs reveals glucosamine- and activity-related effects on gut microbial composition

open access: yesFrontiers in Veterinary Science
The composition of the microbiome influences many aspects of physiology and health, and can be altered by environmental factors, including diet and activity.
Dong Wang   +7 more
doaj   +1 more source

Collagen Hydrolysates as Nutritional Support in Canine Osteoarthritis: A Narrative Review

open access: yesJournal of Animal Physiology and Animal Nutrition, Volume 109, Issue 2, Page 590-600, March 2025.
ABSTRACT Osteoarthritis (OA) is a common disease in dogs with severe impact on their welfare. The multimodal management of OA includes feeding therapeutic diets and nutraceuticals to slow down OA progression. Collagen hydrolysates (CH) are a nutritional supplement that may exert anabolic effects on osteoarthritic joint cartilage as well as disease ...
Niels R. Blees   +5 more
wiley   +1 more source

A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses [PDF]

open access: yes, 1993
The primary structure of the peptidoglycan and the teichoic acids of two coryneform isolates from the surface flora of French cooked cheeses, CNRZ 925 and CNRZ 926, have been determined.
Accolas, Jean-Pierre   +3 more
core  

A Systematic Targeted Genetic Screen Identifies Proteins Involved in Cytoadherence of the Malaria Parasite P. falciparum

open access: yesMolecular Microbiology, Volume 123, Issue 4, Page 330-343, April 2025.
In silico workflow for selection of genes targeted in this study. We have identified a number of proteins involved in host cell modification by malaria parasites. Furthermore, we highlight a number of genes that appear to be essential for blood‐stage survival of these parasites.
Nina Küster   +4 more
wiley   +1 more source

Glucosamine-mediated immunomodulation after stroke is sexually dimorphic

open access: yesBrain, Behavior, & Immunity - Health, 2020
Growing evidence suggests that galectin-3 (Gal-3) is instrumental in orchestrating innate immune response and microglia activation following different brain pathologies. However, its role remains controversial. We recently showed that a readily available
Reza Rahimian   +4 more
doaj  

Cellodextrin Metabolism and Phosphotransferase System‐Catalyzed Uptake in Enterococcus faecalis

open access: yesMolecular Microbiology, Volume 123, Issue 4, Page 378-391, April 2025.
In an infectious context, β‐glucoside metabolism is highly induced in Enterococcus faecalis. Our work demonstrates that this bacterium possesses a network of multiple PTS transporters dedicated to the transport of cellobiose and cellodextrins. The genes encoding the proteins involved in this metabolism are clustered within a single locus in the E ...
Victor Combret   +8 more
wiley   +1 more source

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