Results 21 to 30 of about 19,221 (177)

Extra virgin olive oil use is associated with improved post-prandial blood glucose and LDL cholesterol in healthy subjects [PDF]

open access: yes, 2015
Extra virgin olive oil (EVOO) is a key component of the Mediterranean diet and seems to account for the protective effect against cardiovascular disease.
ANGELICO, Francesco   +10 more
core   +1 more source

Effect of Oral Nutritional Supplements with Sucromalt and Isomaltulose versus Standard Formula on Glycaemic Index, Entero-Insular Axis Peptides and Subjective Appetite in Patients with Type 2 Diabetes: A Randomised Cross-Over Study [PDF]

open access: yes, 2019
Oral diabetes-specific nutritional supplements (ONS-D) induce favourable postprandial responses in subjects with type 2 diabetes (DM2), but they have not been correlated yet with incretin release and subjective appetite (SA).
Angarita Dávila, Lisse Chiquinquira   +10 more
core   +2 more sources

HNF4A mutation: switch from hyperinsulinaemic hypoglycaemia to maturity-onset diabetes of the young, and incretin response [PDF]

open access: yes, 2014
This is a freely-available open access publication. Please cite the published version which is available via the DOI link in this recordHepatocyte nuclear factor 4α (HNF4A) is a member of the nuclear receptor family of ligand-activated transcription ...
Alberti   +19 more
core   +1 more source

Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]

open access: yes, 2017
Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu   +4 more
core   +5 more sources

Glucose‐dependent insulinotropic polypeptide deficiency reduced fat accumulation and insulin resistance, but deteriorated bone loss in ovariectomized mice

open access: yesJournal of Diabetes Investigation, 2019
Given the established roles of glucose‐dependent insulinotropic polypeptide (GIP) in promoting fat storage and bone formation, we assessed the contribution of GIP to obesity and osteopenia in ovariectomized mice with a gene encoding green fluorescent ...
Satoko Shimazu‐Kuwahara   +9 more
doaj   +1 more source

Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

open access: yeseLife, 2021
Glucose-dependent insulinotropic polypeptide (GIP) is a peptide hormone that exerts crucial metabolic functions by binding and activating its cognate receptor, GIPR.
Fenghui Zhao   +17 more
doaj   +1 more source

Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]

open access: yes, 2011
Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Christ-Crain, Mirjam   +10 more
core   +1 more source

The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively. [PDF]

open access: yes, 2014
Background and Objectives: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are important regulators of insulin secretion, and their functional loss is an early characteristic of type 2 diabetes mellitus (T2DM ...
Ahmed, HA   +7 more
core   +6 more sources

Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: Effects on weight loss and safety in adults with overweight or obesity

open access: yesMolecular Metabolism, 2023
Objective: Glucagon/glucagon-like peptide-1 (GLP-1) receptor co-agonists may provide greater weight loss than agonists targeting the GLP-1 receptor alone.
Martin Haljeta Friedrichsen   +6 more
doaj   +1 more source

Metabolic effects of diets differing in glycaemic index depend on age and endogenous GIP [PDF]

open access: yes, 2009
Aims/hypothesis High- vs low-glycaemic index (GI) diets unfavourably affect body fat mass and metabolic markers in rodents. Different effects of these diets could be age-dependent, as well as mediated, in part, by carbohydrate-induced stimulation of ...
A. Abdelrahman   +45 more
core   +1 more source

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