Results 101 to 110 of about 67,753 (222)

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel, Francis Poirier‐Gravel, Marie‐Ève Paré, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Dominique Michaud, Marc‐André D'Aoust   +9 more
wiley   +1 more source

Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle.

PLoS ONE, 2015
Cannabinoid CB1 receptors peripherally modulate energy metabolism. Here, we investigated the role of CB1 receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle.
Sergio Arrabal, Miguel Angel Lucena, Miren Josune Canduela, Almudena Ramos-Uriarte, Patricia Rivera, Antonia Serrano, Francisco Javier Pavón, Juan Decara, Antonio Vargas, Elena Baixeras, Mercedes Martín-Rufián, Javier Márquez, Pedro Fernández-Llébrez, Baukje De Roos, Pedro Grandes, Fernando Rodríguez de Fonseca, Juan Suárez   +16 more
doaj   +1 more source

Modulating the activity of the APC/C regulator SISAMBA improves the sugar and antioxidant content of tomato fruits

Plant Biotechnology Journal, EarlyView.
Summary The Anaphase‐Promoting Complex/Cyclosome (APC/C) is an E3 ubiquitin ligase that plays a crucial role in ubiquitin‐dependent proteolysis of key cell cycle regulators, which is completed by the 26S proteasome. Previously, SAMBA, a plant‐specific regulator of the APC/C, was identified in Arabidopsis as a critical factor controlling organ size ...
Perla Novais de Oliveira, Leonardo Perez de Souza, Pedro Boscariol Ferreira, Jean Phillippe Mauxion, Luis Felipe Correa da Silva, Ana Isabela Chang, Marina de Lyra Soriano Saleme, Feng Zhu, Sara Selma García, Herman De Beukelaer, Marina C. M. Martins, Laise Rosado‐Souza, Lilian Ellen Pino, Norbert Bollier, Lázaro Eustáquio Pereira Peres, Klaas Vandepoele, Alain Goossens, Nathalie Gonzalez, Alisdair R. Fernie, Nubia Barbosa Eloy   +19 more
wiley   +1 more source

6-BA Delays the Senescence of Postharvest Cabbage Leaves by Inhibiting Respiratory Metabolism

Foods
6-BA, a small molecule compound of cytokinins, has been proven to delay leaf senescence in different species, including Chinese flowering cabbage; however, its specific mechanism remains relatively unknown. In this study, the application of external 6-BA
Cimei Wang, Yingying Yang, Jieting Yu, Zongli Liu, Wei Wei, Jianye Chen, Jianhua Zhu, Riming Huang   +7 more
doaj   +1 more source

Cell death‐inducing DNA fragmentation factor alpha (DFFA)‐like effectors (CIDEs) improve lipid droplet (LD) formation and oil accumulation in plant tissues

Plant Biotechnology Journal, EarlyView.
Summary The cell death‐inducing DNA fragmentation factor alpha (DFFA)‐like effectors (CIDEs), including CIDEA, CIDEB and CIDEC, regulate the number and size of lipid droplets (LDs) in vertebrates. However, no homologue of CIDE has been reported in plants.
Yao Xiong, Caiyi Sun, Yuyan Xiang, Yuqing Li, Liang Guo, Shaoping Lu   +5 more
wiley   +1 more source

Contextualized Metabolic Modelling Revealed Factors Affecting Isoflavone Accumulation in Soybean Seeds

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoflavones, secondary metabolites with numerous health benefits, are predominantly found in legume seeds, especially soybean; however, their contents in domesticated soybean seeds are highly variable. Wild soybeans are known for higher seed isoflavone contents than cultivars. Here we used experimental and modelling approaches on wild soybean (
Carolina A. Contador, Ailin Liu, Ming‐Sin Ng, Yee‐Shan Ku, Siu H. J. Chan, Hon‐Ming Lam   +5 more
wiley   +1 more source

Sugar phosphate-mediated inhibition of peptidoglycan precursor synthesis

mBio
Antibiotic tolerance, the widespread ability of diverse pathogenic bacteria to sustain viability in the presence of typically bactericidal antibiotics for extended time periods, is an understudied stepping stone toward antibiotic resistance.
Megan R. Keller, Vijay Soni, Megan Brown, Kelly M. Rosch, Anas Saleh, Kyu Rhee, Tobias Dörr   +6 more
doaj   +1 more source

MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect

eLife, 2017
Rapid cellular proliferation in early development and cancer depends on glucose metabolism to fuel macromolecule biosynthesis. Metabolic enzymes are presumed regulators of this glycolysis-driven metabolic program, known as the Warburg effect; however ...
Nataly Shtraizent, Charles DeRossi, Shikha Nayar, Ravi Sachidanandam, Liora S Katz, Adam Prince, Anna P Koh, Adam Vincek, Yoav Hadas, Yujin Hoshida, Donald K Scott, Efrat Eliyahu, Hudson H Freeze, Kirsten C Sadler, Jaime Chu   +14 more
doaj   +1 more source

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

Experimental Physiology, EarlyView.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi, Stacey L. Holman, Melanie R. Bertossa, Ashley S. Meakin, Vicki L. Clifton, Kent L. Thornburg, I. Caroline McMillen, Michael D. Wiese, Mitchell C. Lock, Janna L. Morrison   +9 more
wiley   +1 more source

Genomic dissection of yield components in rice (Oryza sativa L.) using genome‐wide association study and identification of novel genetic factors for yield‐related traits

Agrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract Genome‐wide association study (GWAS) is a powerful method for understanding the associations between phenotype and genomic variations. Given the growing population, increasing yield of rice as a staple food crop is important. Here, a GWAS with 33,839 single nucleotide polymorphisms (SNPs) was carried out to define genomic regions influencing ...
Rahele Panahabadi, Asadollah Ahmadikhah, Naser Farrokhi, Nadali Bagheri   +3 more
wiley   +1 more source