Results 111 to 120 of about 67,753 (222)

Alternative Splicing Regulation in Metabolic Disorders

Obesity Reviews, Volume 26, Issue 9, September 2025.
ABSTRACT Alternative splicing (AS) is a fundamental mechanism for enhancing transcriptome diversity and regulating gene expression, crucial for various cellular processes and the development of complex traits. This review examines the role of AS in metabolic disorders, including obesity, weight loss, dyslipidemias, and metabolic syndrome.
Dorota Kaminska
wiley   +1 more source

Genetic characterization of a brangus-ibage cattle population: biochemical polymorphisms and reproductive efficiency Caracterização genética de uma população de bovinos brangus-ibagé: polimorfismos bioquímicos e eficiência reprodutiva

Ciência Rural, 2000
Biochemical techniques were used to investigate the genetic variability in a Brangus-Ibage population by determining allele frequencies of 18 blood protein systems: Hemogloin beta-Chain (Hb), Albumin (Alb), Amylase (Am), Transferrin (Tf), Carbonic ...
Luiz Ernani Henkes, Lídia Gonzalez Papadopolis, Clara Sabina Steigleder, José Carlos Ferrugem Moraes, Tania de Azevedo Weimer   +4 more
doaj   +1 more source

Glucose‐6‐phosphate isomerase from ehrlich ascites tumor cells: Purification and some properties [PDF]

, 1973
Klaus‐Heinrich Röhm, Friedhelm Schneider   +1 more
openalex   +1 more source

A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis

Plant, Cell &Environment, Volume 48, Issue 9, Page 6458-6472, September 2025.
ABSTRACT Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6‐phosphate: phosphate co‐transporter GPT2 is highly overexpressed, and this coincides with reduced lignin ...
Aditi Subramani Raju, Abira Sahu, Chunliu Zhuo, Wayne K. Versaw, Richard A. Dixon   +4 more
wiley   +1 more source

The Highly Conserved Cys95 Residue of Fructose‐1,6‐Bisphosphatase 1 Mediates the pH‐Driven Structure and Activity of the Enzyme and Photosynthesis

Plant, Cell &Environment, Volume 48, Issue 9, Page 6941-6951, September 2025.
ABSTRACT In Arabidopsis, exposure to microbial volatile compounds promotes thiol reduction of the Cys95 residue of the photosynthetic enzyme fructose‐1,6‐bisphosphatase (cFBP1). Although highly conserved in plants, the Cys95 function still remains unknown. We characterised recombinant wild‐type (WT) cFBP1 and a variant (C95S) in which the Cys95 residue
Samuel Gámez‐Arcas, Edurne Baroja‐Fernández, Francisco José Muñoz, Antonio J. Serrato, Mónica Balsera, Ángela María Sánchez‐López, Abdellatif Bahaji, Jesús Leal‐López, Rafael Jorge León Morcillo, Javier Pozueta‐Romero   +9 more
wiley   +1 more source

Integrative Analyses of Metabolome and Transcriptome Reveals Apocarotenoid and Flavonoid Biosynthesis During Saffron (Crocus sativus L.) Stigmas Development

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
During the development of saffron stigmas, crocetin and flavonoids were primarily synthesized in the early red stage (S1), while crocins were synthesized in the late red stage (S2). The biosynthesis pathways of ABA and picrocrocin were particularly active at anthesis (S3).
Jing Chen, Xuting Xu, Shuhui Yang, Xiaodong Qian, Yuanyuan Tao, Guifen Zhou, Jing Li, Limin Xu, Liqin Li   +8 more
wiley   +1 more source

Efficacy of combination treatment with fingolimod (FTY720) plus pathogenic autoantigen in a glucose-6-phosphate isomerase peptide (GPI325-339)-induced arthritis mouse model.

Biological and Pharmaceutical Bulletin, 2013
Fingolimod (FTY720) is known to have a significant therapeutic effect in various autoimmune disease models. Here, we examined FTY720 in a model of rheumatoid arthritis, induced by immunizing DBA/1 mice with a peptide consisting of residues 325 through ...
Yuya Yoshida, Takumi Tsuji, Sayaka Watanabe, Ayane Matsushima, Y. Matsushima, Rie Banno, T. Fujita, T. Kohno   +7 more
semanticscholar   +1 more source

Two Centrins and Their Posttranslational Modification Modulate the Cell Cycle of Giardia lamblia

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Two Giardia lamblia centrins (Glcents) play a role in cell cycle progression and morphogenesis of Giardia. Both Glcents are substrates of GlSUMO, suggesting a role of SUMOylation in their proper localization. SUMOylation is also involved in regulating vacuole formation in Giardia.
Hye Rim Yeo, Mee Young Shin, Juri Kim, Soon‐Jung Park   +3 more
wiley   +1 more source

Astrocyte in Neurological Disease: Pathogenesis and Therapy

MedComm, Volume 6, Issue 8, August 2025.
This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang, Aoyang Long, Lingjia Hao, Zilin Shi, Mengqi Zhang   +4 more
wiley   +1 more source

Mitochondrial Quality Control in Health and Disease

MedComm, Volume 6, Issue 8, August 2025.
Mitochondrial quality control (MQC) maintains cellular homeostasis by coordinating various processes such as fission, fusion, mitophagy, and mitochondria‐regulated cell death. Dysregulation of these mechanisms plays a key role in the development of many human diseases.
Lin Ye, Xinzhi Fu, Qi Li
wiley   +1 more source