Results 141 to 150 of about 64,864 (253)

Molecular Responses to Climate Change: How Warming and Acidification Reshape the Proteome and Phosphoproteome of the Endangered Mira Chub

Ecology and Evolution, Volume 16, Issue 3, March 2026.
ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno, Jonas Grossmann, Laura Kunz, Antje Dittmann, Vitor C. Sousa, Romana Santos   +5 more
wiley   +1 more source

Effects of Macromolecular Crowding on the Refolding of Glucose- 6-phosphate Dehydrogenase and Protein Disulfide Isomerase [PDF]

, 2001
Jian Li, Sen Zhang, Chih-chen Wang
openalex   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Genome‐wide association study identifies consistent genomic loci for yield and nutritional quality in Ethiopian sorghum landraces

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Identifying genomic regions linked to yield and quality is crucial for sorghum (Sorghum bicolor L.) improvement, but limited studies on its genome and diversity hinder breeding efforts. This study aimed to identify phenotypic variance and common quantitative trait nucleotides (QTNs) associated with genomic regions linked with grain yield and ...
Chalachew Endalamaw, Temesgen M. Menamo, Firezer G. Kebede, Zeleke Wondimu, Hailekiros Tadesse Tekle, Kwame Shamuyarira, Angeline Jacoby, Maryke Tine Labuschagne   +7 more
wiley   +1 more source

Esculetin inhibits liver cancer by targeting glucose-6-phosphate isomerase mediated glycolysis

Biomedicine & Pharmacotherapy
Liver cancer is challenging to detect in its early stages, and the global incidence rate and mortality associated with this disease have reached alarming levels. Currently, treatment options for liver cancer are limited, and there is a significant lack of safe and effective therapeutic agents.
Zongchao, Hong, Jingbo, Wang, Baodan, Hu, Xin, Tu, Jin, Yang, Wanjin, Sun, Xueyun, Duan   +6 more
openaire   +2 more sources

Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target

Aging Cell, Volume 25, Issue 3, March 2026.
By a global proteomic profiling of senescent human BJ fibroblasts induced by ionizing radiation, key cellular features required for the survival of senescent fibroblasts were revealed, and pyruvate dehydrogenase was demonstrated as a potent senolytic target for selectively eliminating senescent normal cells, particularly the therapy‐induced senescent ...
Mingzhu Zhang, Ziqi Hu, Shengwen Piao, Yingrui Song, Ying Jia, Jiaxing Liu, Ning Zhao, An Liu, Songbin Fu, Wenjing Sun, Hui Xu, Yu Yang, Steven P. Gygi, Chunshui Zhou   +13 more
wiley   +1 more source

Mechanisms of brain damage caused by inorganic fluoride using proteomics-based techniques

环境与职业医学
BackgroundChronic excessive exposure to fluoride can cause damage to the central nervous system and a certain degree of learning and memory impairment. However, the associated mechanism is not yet clear and further exploration is needed.
Xiao ZHOU, Wen WAN, Dewen JIANG, Fujun AI, Ling YE, Minghai LIU, Yi ZHANG, Yanjie LIU   +7 more
doaj   +1 more source

Comparison of Three In-House Real PCR Assays Targeting Kinetoplast DNA, the Small Subunit Ribosomal RNA Gene and the Glucose-6-Phosphate Isomerase Gene for the Detection of Leishmania spp. in Human Serum. [PDF]

Pathogens, 2021
Tanida K, Balczun C, Hahn A, Veit A, Nickel B, Poppert S, Scheid PL, Hagen RM, Frickmann H, Loderstädt U, Tannich E.   +10 more
europepmc   +1 more source

Partial Purification and Characterization of Glucose-6-phosphate Isomerase from Dictyostelium discoideum [PDF]

, 1981
D. A. Thomas
openalex   +1 more source

Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia, Cesar Augusto Roque‐Borda, Fernando Rogério Pavan, Marlus Chorilli   +3 more
wiley   +1 more source